FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2076806146> ?p ?o ?g. }

• W2076806146 endingPage "40" @default.
• W2076806146 startingPage "36" @default.
• W2076806146 abstract "Tendo em vista a grande frequência de alterações cromossômicas, seja nos casais com quadros de abortamento de repetição ou nos fetos abortados, uma possibilidade para o tratamento para esses pacientes seria o uso de tratamentos de reprodução assistida, associados ao diagnóstico genético pré-implantacional (PGD) com a técnica de hibridização genética comparativa por array (array-CGH), para a transferência apenas de embriões geneticamente normais. O objetivo desta revisão é avaliar se é possível melhorar o prognóstico gestacional, com redução do número de perdas e o do tempo para conseguir uma gestação saudável, desses casais com aborto de repetição ao usarem o PDG por array-CGH. Foram executadas duas revisões bibliográficas dos últimos 10 anos, a primeira relacionando o uso do PGD nos casos de aborto de repetição e a outra com o uso do array-CGH e PGD. A literatura, apesar de discordante quanto à real eficácia do PGD nos casos de aborto de repetição, tende a se mostrar favorável ao uso dessa técnica, da mesma forma que o método de fluorescence in situ hybridization (Fish) é inferior a array-CGH para o PGD. Dessa forma, apesar de ser uma técnica promissora para casais com AR, o PGD com array-CGH necessita de mais estudos que comprovem sua real eficácia. Given the high frequency of chromosomal abnormalities, either in couples with recurrent miscarriage or in aborted fetuses, a possibility for treatment for these patients is the use of assisted reproduction treatment, associated with preimplantation genetic diagnosis (PGD) with technique by array comparative genomic hybridization (array-CGH), to transfer only genetically normal embryos. The aim of this review is to assess the feasibility of improving the prognosis of pregnancy, reducing the number of losses and the time to achieve a healthy pregnancy, for couples with recurrent abortion when using PDG with array-CGH. Two literature reviews were performed for the last 10 years, the first relating the use of PGD and recurrent miscarriage, and the other using the array-CGH and PGD. The literature, although discordant about the real efficacy of PGD in cases of recurrent abortion, tends to show favorable to use this technique, just as the method of array-CGH shows to be better than Fish (fluorescence in-situ hybridization) for PGD. Thus, despite of being a promising technique for couples with RA, the use of PDG with array-CGH needs more study to prove its actual effectiveness." @default.
• W2076806146 created "2016-06-24" @default.
• W2076806146 creator A5062957702 @default.
• W2076806146 creator A5091886789 @default.
• W2076806146 date "2013-01-01" @default.
• W2076806146 modified "2023-09-27" @default.
• W2076806146 title "O uso do diagnóstico genético pré-implantacional em pacientes com aborto de repetição: revisão do uso da técnica de array-CGH" @default.
• W2076806146 cites W1552457466 @default.
• W2076806146 cites W1852269776 @default.
• W2076806146 cites W1977964871 @default.
• W2076806146 cites W1979923278 @default.
• W2076806146 cites W2007174121 @default.
• W2076806146 cites W2019873917 @default.
• W2076806146 cites W2037812077 @default.
• W2076806146 cites W2043019860 @default.
• W2076806146 cites W2055447796 @default.
• W2076806146 cites W2070885598 @default.
• W2076806146 cites W2073005651 @default.
• W2076806146 cites W2082068268 @default.
• W2076806146 cites W2089212294 @default.
• W2076806146 cites W2120207855 @default.
• W2076806146 cites W2122377185 @default.
• W2076806146 cites W2132197237 @default.
• W2076806146 cites W2133566860 @default.
• W2076806146 cites W2133677971 @default.
• W2076806146 cites W2145786802 @default.
• W2076806146 cites W2147539249 @default.
• W2076806146 cites W2147787069 @default.
• W2076806146 cites W2153289629 @default.
• W2076806146 cites W2153911304 @default.
• W2076806146 cites W2155683328 @default.
• W2076806146 cites W2160524881 @default.
• W2076806146 cites W2170141366 @default.
• W2076806146 cites W74223119 @default.
• W2076806146 doi "https://doi.org/10.1016/j.recli.2013.05.004" @default.
• W2076806146 hasPublicationYear "2013" @default.
• W2076806146 type Work @default.
• W2076806146 sameAs 2076806146 @default.
• W2076806146 citedByCount "0" @default.
• W2076806146 crossrefType "journal-article" @default.
• W2076806146 hasAuthorship W2076806146A5062957702 @default.
• W2076806146 hasAuthorship W2076806146A5091886789 @default.
• W2076806146 hasBestOaLocation W20768061461 @default.
• W2076806146 hasConcept C2909208804 @default.
• W2076806146 hasConcept C29456083 @default.
• W2076806146 hasConcept C505870484 @default.
• W2076806146 hasConcept C71924100 @default.
• W2076806146 hasConcept C86803240 @default.
• W2076806146 hasConceptScore W2076806146C2909208804 @default.
• W2076806146 hasConceptScore W2076806146C29456083 @default.
• W2076806146 hasConceptScore W2076806146C505870484 @default.
• W2076806146 hasConceptScore W2076806146C71924100 @default.
• W2076806146 hasConceptScore W2076806146C86803240 @default.
• W2076806146 hasIssue "1" @default.
• W2076806146 hasLocation W20768061461 @default.
• W2076806146 hasOpenAccess W2076806146 @default.
• W2076806146 hasPrimaryLocation W20768061461 @default.
• W2076806146 hasRelatedWork W1995515455 @default.
• W2076806146 hasRelatedWork W1999344589 @default.
• W2076806146 hasRelatedWork W2039318446 @default.
• W2076806146 hasRelatedWork W2080531066 @default.
• W2076806146 hasRelatedWork W2748952813 @default.
• W2076806146 hasRelatedWork W2789448498 @default.
• W2076806146 hasRelatedWork W2899084033 @default.
• W2076806146 hasRelatedWork W3031052312 @default.
• W2076806146 hasRelatedWork W3032375762 @default.
• W2076806146 hasRelatedWork W3108674512 @default.
• W2076806146 hasVolume "28" @default.
• W2076806146 isParatext "false" @default.
• W2076806146 isRetracted "false" @default.
• W2076806146 magId "2076806146" @default.
• W2076806146 workType "article" @default.