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• W2076812204 abstract "The amino terminal of human P51/TAp63, a P53 homologue, possesses a transactivation domain involved in the activation of its target genes by binding to DNA elements responsive to the p53 protein family. Using a series of amino terminal deletions, the transactivation domain was mapped between amino acid residues 50 to 69. This domain also regulates protein stability in a proteasome-dependent manner, and Ser51 and Ser68 were found to be essential for this stability. Our results suggest that P51 activity is greatly affected by protein stability." @default.
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• W2076812204 date "2001-05-01" @default.
• W2076812204 modified "2023-10-11" @default.
• W2076812204 title "Regulatory Domain of Protein Stability of Human P51/TAP63, a P53 Homologue" @default.
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• W2076812204 doi "https://doi.org/10.1006/bbrc.2001.4905" @default.
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