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Matches in SemOpenAlex for { <https://semopenalex.org/work/W207682006> ?p ?o ?g. }

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• W207682006 abstract "A heat-stable enterotoxin (STp) consisting of 18 amino acid residues including 6 half-cystine residues is produced by a porcine strain of enterotoxigenic Escherichia coli. Analogs of STp with replacements of single residues at each from positions 5 to 17 by the corresponding D-amino acid residue were synthesized by a solid-phase method. Of these analogs, [D-Cys5]-STp[5-17] showed the same biological properties as STp[5-17]. Moreover, its activity to cause fluid accumulation in suckling mouse lasts more than 24 hours, whereas the activity of STp[5-17] decreases after 6-10 hours. These results indicate that the action of the analog [D-Cys5]-STp[5-17] is strongly agonistic to that of the native ST." @default.
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• W207682006 date "1989-05-01" @default.
• W207682006 modified "2023-09-30" @default.
• W207682006 title "A long-acting heat-stable enterotoxin analog of enterotoxigenic with a single D-amino acid" @default.
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• W207682006 doi "https://doi.org/10.1016/0006-291x(89)91585-4" @default.
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