FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2076835776> ?p ?o ?g. }

• W2076835776 endingPage "560" @default.
• W2076835776 startingPage "554" @default.
• W2076835776 abstract "The current study sets out to characterize the intracellular localization of the platelet-type 12S-lipoxygenase (12-LO), an enzyme involved in angiotensin-II induced signaling in vascular smooth muscle cells (VSMC). Immunohistochemical analysis of VSMC in vitro or human umbilical arteries in vivo showed a clear cytoplasmic localization. On immunogold electron microscopy, 12-LO was found primarily associated with cytoplasmic VSMC muscle fibrils. Upon angiotensin-II treatment of cultured VSMC, immunoprecipitated 12-LO was found bound to alpha-actin, a component of the cytoplasmic myofilaments. 12-LO/alpha-actin binding was blocked by VSMC pretreatment with the 12-LO inhibitors, baicalien or esculetine and the protein synthesis inhibitor, cycloheximide. Moreover, the binding of 12-LO to alpha-actin was not associated with 12-LO serine or tyrosine phosphorylation. These observations suggest a previously unrecognized angiotensin-II dependent protein interaction in VSMC through which 12-LO protein may be trafficked, for yet undiscovered purposes towards the much more abundantly expressed cytoskeletal protein alpha-actin." @default.
• W2076835776 created "2016-06-24" @default.
• W2076835776 creator A5028457669 @default.
• W2076835776 creator A5029346886 @default.
• W2076835776 creator A5037852773 @default.
• W2076835776 creator A5042599481 @default.
• W2076835776 creator A5044255489 @default.
• W2076835776 creator A5081914962 @default.
• W2076835776 creator A5083079541 @default.
• W2076835776 creator A5088392978 @default.
• W2076835776 date "2007-05-01" @default.
• W2076835776 modified "2023-10-14" @default.
• W2076835776 title "12S-lipoxygenase protein associates with α-actin fibers in human umbilical artery vascular smooth muscle cells" @default.
• W2076835776 cites W1965700036 @default.
• W2076835776 cites W1970666689 @default.
• W2076835776 cites W1971812188 @default.
• W2076835776 cites W1992575030 @default.
• W2076835776 cites W1997486430 @default.
• W2076835776 cites W2011666432 @default.
• W2076835776 cites W2029457344 @default.
• W2076835776 cites W2039974532 @default.
• W2076835776 cites W2046149557 @default.
• W2076835776 cites W2046331114 @default.
• W2076835776 cites W2049099038 @default.
• W2076835776 cites W2064766999 @default.
• W2076835776 cites W2084997952 @default.
• W2076835776 cites W2085371930 @default.
• W2076835776 cites W2087027217 @default.
• W2076835776 cites W2115050270 @default.
• W2076835776 cites W2126533417 @default.
• W2076835776 cites W2132658963 @default.
• W2076835776 cites W2132845622 @default.
• W2076835776 cites W2135178410 @default.
• W2076835776 cites W2139588799 @default.
• W2076835776 cites W2168996156 @default.
• W2076835776 cites W2403367861 @default.
• W2076835776 cites W3146714045 @default.
• W2076835776 cites W4293247451 @default.
• W2076835776 doi "https://doi.org/10.1016/j.bbrc.2007.03.012" @default.
• W2076835776 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17379189" @default.
• W2076835776 hasPublicationYear "2007" @default.
• W2076835776 type Work @default.
• W2076835776 sameAs 2076835776 @default.
• W2076835776 citedByCount "5" @default.
• W2076835776 countsByYear W20768357762013 @default.
• W2076835776 countsByYear W20768357762019 @default.
• W2076835776 countsByYear W20768357762021 @default.
• W2076835776 crossrefType "journal-article" @default.
• W2076835776 hasAuthorship W2076835776A5028457669 @default.
• W2076835776 hasAuthorship W2076835776A5029346886 @default.
• W2076835776 hasAuthorship W2076835776A5037852773 @default.
• W2076835776 hasAuthorship W2076835776A5042599481 @default.
• W2076835776 hasAuthorship W2076835776A5044255489 @default.
• W2076835776 hasAuthorship W2076835776A5081914962 @default.
• W2076835776 hasAuthorship W2076835776A5083079541 @default.
• W2076835776 hasAuthorship W2076835776A5088392978 @default.
• W2076835776 hasConcept C105702510 @default.
• W2076835776 hasConcept C125705527 @default.
• W2076835776 hasConcept C130861313 @default.
• W2076835776 hasConcept C134018914 @default.
• W2076835776 hasConcept C142669718 @default.
• W2076835776 hasConcept C1491633281 @default.
• W2076835776 hasConcept C170493617 @default.
• W2076835776 hasConcept C174054327 @default.
• W2076835776 hasConcept C185592680 @default.
• W2076835776 hasConcept C190062978 @default.
• W2076835776 hasConcept C2779395532 @default.
• W2076835776 hasConcept C2908929049 @default.
• W2076835776 hasConcept C2992686903 @default.
• W2076835776 hasConcept C2993400109 @default.
• W2076835776 hasConcept C30030713 @default.
• W2076835776 hasConcept C55493867 @default.
• W2076835776 hasConcept C86803240 @default.
• W2076835776 hasConcept C87555872 @default.
• W2076835776 hasConcept C95444343 @default.
• W2076835776 hasConceptScore W2076835776C105702510 @default.
• W2076835776 hasConceptScore W2076835776C125705527 @default.
• W2076835776 hasConceptScore W2076835776C130861313 @default.
• W2076835776 hasConceptScore W2076835776C134018914 @default.
• W2076835776 hasConceptScore W2076835776C142669718 @default.
• W2076835776 hasConceptScore W2076835776C1491633281 @default.
• W2076835776 hasConceptScore W2076835776C170493617 @default.
• W2076835776 hasConceptScore W2076835776C174054327 @default.
• W2076835776 hasConceptScore W2076835776C185592680 @default.
• W2076835776 hasConceptScore W2076835776C190062978 @default.
• W2076835776 hasConceptScore W2076835776C2779395532 @default.
• W2076835776 hasConceptScore W2076835776C2908929049 @default.
• W2076835776 hasConceptScore W2076835776C2992686903 @default.
• W2076835776 hasConceptScore W2076835776C2993400109 @default.
• W2076835776 hasConceptScore W2076835776C30030713 @default.
• W2076835776 hasConceptScore W2076835776C55493867 @default.
• W2076835776 hasConceptScore W2076835776C86803240 @default.
• W2076835776 hasConceptScore W2076835776C87555872 @default.
• W2076835776 hasConceptScore W2076835776C95444343 @default.
• W2076835776 hasIssue "3" @default.
• W2076835776 hasLocation W20768357761 @default.
• W2076835776 hasLocation W20768357762 @default.
• W2076835776 hasOpenAccess W2076835776 @default.

• next