FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2076872682> ?p ?o ?g. }

• W2076872682 endingPage "169" @default.
• W2076872682 startingPage "161" @default.
• W2076872682 abstract "Glial calcium (Ca 2+ ) waves constitute a means to spread signals between glial cells and to neighboring neurons and blood vessels. These waves occur spontaneously in Bergmann glia (BG) of the mouse cerebellar cortex in vivo. Here, we tested three hypotheses: (1) aging and reduced blood oxygen saturation alters wave activity; (2) glial Ca 2+ waves change cerebral oxygen metabolism; and (3) neuronal and glial wave activity is correlated. We used two-photon microscopy in the cerebellar cortexes of adult (8- to 15-week-old) and aging (48- to 80-week-old) ketamine-anesthetized mice after bolus loading with OGB-1/AM and SR101. We report that the occurrence of spontaneous waves is 20 times more frequent in the cerebellar cortex of aging as compared with adult mice, which correlated with a reduction in resting brain oxygen tension. In adult mice, spontaneous glial wave activity increased on reducing resting brain oxygen tension, and ATP-evoked glial waves reduced the tissue O 2 tension. Finally, although spontaneous Purkinje cell (PC) activity was not associated with increased glia wave activity, spontaneous glial waves did affect intracellular Ca 2+ activity in PCs. The increased wave activity during aging, as well as low resting brain oxygen tension, suggests a relationship between glial waves, brain energy homeostasis, and pathology." @default.
• W2076872682 created "2016-06-24" @default.
• W2076872682 creator A5001609953 @default.
• W2076872682 creator A5018122030 @default.
• W2076872682 creator A5019685160 @default.
• W2076872682 creator A5023746085 @default.
• W2076872682 date "2012-12-05" @default.
• W2076872682 modified "2023-10-17" @default.
• W2076872682 title "Spontaneous Calcium Waves in Bergman Glia Increase with Age and Hypoxia and may Reduce Tissue Oxygen" @default.
• W2076872682 cites W1971125401 @default.
• W2076872682 cites W1981723221 @default.
• W2076872682 cites W2009538509 @default.
• W2076872682 cites W2012806642 @default.
• W2076872682 cites W2013845069 @default.
• W2076872682 cites W2019016175 @default.
• W2076872682 cites W2023019924 @default.
• W2076872682 cites W2027616725 @default.
• W2076872682 cites W2028036419 @default.
• W2076872682 cites W2046400378 @default.
• W2076872682 cites W2048270592 @default.
• W2076872682 cites W2063093203 @default.
• W2076872682 cites W2065283157 @default.
• W2076872682 cites W2067550100 @default.
• W2076872682 cites W2067846556 @default.
• W2076872682 cites W2067988047 @default.
• W2076872682 cites W2100486119 @default.
• W2076872682 cites W2103065509 @default.
• W2076872682 cites W2128632634 @default.
• W2076872682 cites W2133851684 @default.
• W2076872682 cites W2146324610 @default.
• W2076872682 cites W2150820507 @default.
• W2076872682 cites W2156586719 @default.
• W2076872682 cites W2163234334 @default.
• W2076872682 cites W4245176872 @default.
• W2076872682 cites W4245552230 @default.
• W2076872682 doi "https://doi.org/10.1038/jcbfm.2012.175" @default.
• W2076872682 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3564203" @default.
• W2076872682 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23211964" @default.
• W2076872682 hasPublicationYear "2012" @default.
• W2076872682 type Work @default.
• W2076872682 sameAs 2076872682 @default.
• W2076872682 citedByCount "43" @default.
• W2076872682 countsByYear W20768726822012 @default.
• W2076872682 countsByYear W20768726822013 @default.
• W2076872682 countsByYear W20768726822014 @default.
• W2076872682 countsByYear W20768726822015 @default.
• W2076872682 countsByYear W20768726822016 @default.
• W2076872682 countsByYear W20768726822017 @default.
• W2076872682 countsByYear W20768726822018 @default.
• W2076872682 countsByYear W20768726822019 @default.
• W2076872682 countsByYear W20768726822020 @default.
• W2076872682 countsByYear W20768726822021 @default.
• W2076872682 countsByYear W20768726822022 @default.
• W2076872682 countsByYear W20768726822023 @default.
• W2076872682 crossrefType "journal-article" @default.
• W2076872682 hasAuthorship W2076872682A5001609953 @default.
• W2076872682 hasAuthorship W2076872682A5018122030 @default.
• W2076872682 hasAuthorship W2076872682A5019685160 @default.
• W2076872682 hasAuthorship W2076872682A5023746085 @default.
• W2076872682 hasBestOaLocation W20768726821 @default.
• W2076872682 hasConcept C169760540 @default.
• W2076872682 hasConcept C178790620 @default.
• W2076872682 hasConcept C185592680 @default.
• W2076872682 hasConcept C2779652256 @default.
• W2076872682 hasConcept C2780884517 @default.
• W2076872682 hasConcept C2781041448 @default.
• W2076872682 hasConcept C2992333117 @default.
• W2076872682 hasConcept C2993207723 @default.
• W2076872682 hasConcept C529278444 @default.
• W2076872682 hasConcept C540031477 @default.
• W2076872682 hasConcept C7836513 @default.
• W2076872682 hasConcept C86803240 @default.
• W2076872682 hasConceptScore W2076872682C169760540 @default.
• W2076872682 hasConceptScore W2076872682C178790620 @default.
• W2076872682 hasConceptScore W2076872682C185592680 @default.
• W2076872682 hasConceptScore W2076872682C2779652256 @default.
• W2076872682 hasConceptScore W2076872682C2780884517 @default.
• W2076872682 hasConceptScore W2076872682C2781041448 @default.
• W2076872682 hasConceptScore W2076872682C2992333117 @default.
• W2076872682 hasConceptScore W2076872682C2993207723 @default.
• W2076872682 hasConceptScore W2076872682C529278444 @default.
• W2076872682 hasConceptScore W2076872682C540031477 @default.
• W2076872682 hasConceptScore W2076872682C7836513 @default.
• W2076872682 hasConceptScore W2076872682C86803240 @default.
• W2076872682 hasIssue "2" @default.
• W2076872682 hasLocation W20768726821 @default.
• W2076872682 hasLocation W20768726822 @default.
• W2076872682 hasLocation W20768726823 @default.
• W2076872682 hasLocation W20768726824 @default.
• W2076872682 hasOpenAccess W2076872682 @default.
• W2076872682 hasPrimaryLocation W20768726821 @default.
• W2076872682 hasRelatedWork W1971533408 @default.
• W2076872682 hasRelatedWork W2023057624 @default.
• W2076872682 hasRelatedWork W2037407575 @default.
• W2076872682 hasRelatedWork W2048583863 @default.
• W2076872682 hasRelatedWork W2067283995 @default.
• W2076872682 hasRelatedWork W2072802414 @default.
• W2076872682 hasRelatedWork W2077023743 @default.

• next