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• W2076875222 abstract "Batch kinetics of polyhydroxybutyrate (PHB) synthesis in a bioreactor under controlled conditions of pH and dissolved oxygen gave a biomass of 14 g l−1 with a PHB concentration of 6.1 g l−1 in 60 h. The data of the batch kinetics was used to develop a mathematical model, which was then extrapolated to fed-batch by incorporating the dilution due to substrate feeding. Offline computer simulation of the fed-batch model was done to develop the nutrient feeding strategies in the fed-batch cultivation. Fed-batch strategies with constant feeding of only nitrogen and constant feeding of both nitrogen and fructose were tried. Constant feeding strategy for nitrogen and fructose gave a better PHB production rate of 0.56 g h−1 over the value obtained in batch cultivation (PHB production rate – 0.4 g h−1)." @default.
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• W2076875222 date "2008-04-01" @default.
• W2076875222 modified "2023-10-11" @default.
• W2076875222 title "Fed-batch cultivation of Wautersia eutropha" @default.
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• W2076875222 doi "https://doi.org/10.1016/j.biortech.2007.03.034" @default.
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