FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2076880479> ?p ?o ?g. }

• W2076880479 endingPage "551" @default.
• W2076880479 startingPage "543" @default.
• W2076880479 abstract "Transcriptional regulation of the p53 tumour suppressor gene plays an important role in the control of the expression of various target genes involved in the DNA damage response. However, the molecular basis of this regulation remains obscure. In the present study we demonstrate that RREB-1 (Ras-responsive-element-binding protein-1) efficiently binds to the p53 promoter via the p53 core promoter element and transactivates p53 expression. Silencing of RREB-1 significantly reduces p53 expression at both the mRNA and the protein levels. Notably, disruption of RREB-1-mediated p53 transcription suppresses the expression of the p53 target genes. We also show that, upon exposure to genotoxic stress, RREB-1 controls apoptosis in a p53-dependent manner. These findings provide evidence that RREB-1 participates in modulating p53 transcription in response to DNA damage." @default.
• W2076880479 created "2016-06-24" @default.
• W2076880479 creator A5030946091 @default.
• W2076880479 creator A5031695335 @default.
• W2076880479 creator A5054622071 @default.
• W2076880479 creator A5074043103 @default.
• W2076880479 creator A5079742854 @default.
• W2076880479 creator A5091623593 @default.
• W2076880479 date "2009-08-27" @default.
• W2076880479 modified "2023-10-16" @default.
• W2076880479 title "DNA damage signalling recruits RREB-1 to the p53 tumour suppressor promoter" @default.
• W2076880479 cites W1494864623 @default.
• W2076880479 cites W1650797637 @default.
• W2076880479 cites W1968220278 @default.
• W2076880479 cites W1971195681 @default.
• W2076880479 cites W1976873804 @default.
• W2076880479 cites W1993720756 @default.
• W2076880479 cites W2004067791 @default.
• W2076880479 cites W2007579725 @default.
• W2076880479 cites W2011912935 @default.
• W2076880479 cites W2012711829 @default.
• W2076880479 cites W2014170738 @default.
• W2076880479 cites W2017052599 @default.
• W2076880479 cites W2018394492 @default.
• W2076880479 cites W2048657955 @default.
• W2076880479 cites W2051223687 @default.
• W2076880479 cites W2051599584 @default.
• W2076880479 cites W2056530510 @default.
• W2076880479 cites W2063669247 @default.
• W2076880479 cites W2066126643 @default.
• W2076880479 cites W2071198627 @default.
• W2076880479 cites W2074545297 @default.
• W2076880479 cites W2077229666 @default.
• W2076880479 cites W2082724854 @default.
• W2076880479 cites W2083991264 @default.
• W2076880479 cites W2090025028 @default.
• W2076880479 cites W2092675732 @default.
• W2076880479 cites W2099018448 @default.
• W2076880479 cites W2100894466 @default.
• W2076880479 cites W2109056181 @default.
• W2076880479 cites W2112893238 @default.
• W2076880479 cites W2119085116 @default.
• W2076880479 cites W2119885778 @default.
• W2076880479 cites W2120362365 @default.
• W2076880479 cites W2126481808 @default.
• W2076880479 cites W2131613604 @default.
• W2076880479 cites W2144934582 @default.
• W2076880479 cites W2163565167 @default.
• W2076880479 cites W2164234304 @default.
• W2076880479 cites W2419099630 @default.
• W2076880479 cites W4212766227 @default.
• W2076880479 doi "https://doi.org/10.1042/bj20090342" @default.
• W2076880479 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19558368" @default.
• W2076880479 hasPublicationYear "2009" @default.
• W2076880479 type Work @default.
• W2076880479 sameAs 2076880479 @default.
• W2076880479 citedByCount "37" @default.
• W2076880479 countsByYear W20768804792012 @default.
• W2076880479 countsByYear W20768804792013 @default.
• W2076880479 countsByYear W20768804792014 @default.
• W2076880479 countsByYear W20768804792015 @default.
• W2076880479 countsByYear W20768804792016 @default.
• W2076880479 countsByYear W20768804792017 @default.
• W2076880479 countsByYear W20768804792018 @default.
• W2076880479 countsByYear W20768804792019 @default.
• W2076880479 countsByYear W20768804792020 @default.
• W2076880479 countsByYear W20768804792021 @default.
• W2076880479 countsByYear W20768804792022 @default.
• W2076880479 countsByYear W20768804792023 @default.
• W2076880479 crossrefType "journal-article" @default.
• W2076880479 hasAuthorship W2076880479A5030946091 @default.
• W2076880479 hasAuthorship W2076880479A5031695335 @default.
• W2076880479 hasAuthorship W2076880479A5054622071 @default.
• W2076880479 hasAuthorship W2076880479A5074043103 @default.
• W2076880479 hasAuthorship W2076880479A5079742854 @default.
• W2076880479 hasAuthorship W2076880479A5091623593 @default.
• W2076880479 hasConcept C101762097 @default.
• W2076880479 hasConcept C104317684 @default.
• W2076880479 hasConcept C119056186 @default.
• W2076880479 hasConcept C132376346 @default.
• W2076880479 hasConcept C138885662 @default.
• W2076880479 hasConcept C143425029 @default.
• W2076880479 hasConcept C150194340 @default.
• W2076880479 hasConcept C153911025 @default.
• W2076880479 hasConcept C165864922 @default.
• W2076880479 hasConcept C179185449 @default.
• W2076880479 hasConcept C179926584 @default.
• W2076880479 hasConcept C27153228 @default.
• W2076880479 hasConcept C41895202 @default.
• W2076880479 hasConcept C54355233 @default.
• W2076880479 hasConcept C552990157 @default.
• W2076880479 hasConcept C86339819 @default.
• W2076880479 hasConcept C86803240 @default.
• W2076880479 hasConcept C95444343 @default.
• W2076880479 hasConceptScore W2076880479C101762097 @default.
• W2076880479 hasConceptScore W2076880479C104317684 @default.
• W2076880479 hasConceptScore W2076880479C119056186 @default.
• W2076880479 hasConceptScore W2076880479C132376346 @default.

• next