FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2076893246> ?p ?o ?g. }

• W2076893246 endingPage "79" @default.
• W2076893246 startingPage "69" @default.
• W2076893246 abstract "We have reported that dietary fish oil (FO) rich in n−3 PUFA modulates gut contractility. It was further demonstrated that the gut of spontaneously hypertensive rats (SHR) has a depressed contractility response to prostaglandins (PG) compared with normotensive Wistar-Kyoto (WKY) rats. We investigated whether feeding diets supplemented with n−3 PUFA increased gut contractility and restored the depressed prostanoid response in SHR gut. Thirteen-week-old SHR were fed diets containing fat at 5 g/100 g as coconut oil (CO), lard, canola oil containing 10% (w/w) n−3 FA as α-linolenic acid (18∶3n−3), or FO (as HiDHA®, 22∶6n−3) for 12 wk. A control WKY group was fed 5 g/100 g CO in the diet. As confirmed, the SHR CO group had a significantly lower gut response to PGE2 and PGF2α compared with the WKY CO group. Feeding FO increased the maximal contraction response to acetylcholine in the ileum compared with all diets and in the colon compared with lard, and restored the depressed response to PGE2 and PGF2α in the ileum but not the colon of SHR. FO feeding also led to a significant increase in gut total phospholipid n−3 PUFA as DHA (22∶6n−3) with lower n−6 PUFA as arachidonic acid (20∶4n−6). Canola feeding led to a small increase in ileal EPA (20∶5n−3) and DHA and in colonic DHA without affecting contractility. However, there was no change in ileal membrane muscarinic binding properties due to FO feeding. This report confirms that dietary FO increases muscarinic- and eicosanoid receptor-induced contractility in ileum and that the depressed prostanoid response in SHR ileum, but not colon, is restored by tissue incorporation of DHA as the active nutrient." @default.
• W2076893246 created "2016-06-24" @default.
• W2076893246 creator A5018026838 @default.
• W2076893246 creator A5018280281 @default.
• W2076893246 creator A5043951707 @default.
• W2076893246 creator A5048846339 @default.
• W2076893246 creator A5051068014 @default.
• W2076893246 creator A5087320270 @default.
• W2076893246 date "2005-01-01" @default.
• W2076893246 modified "2023-10-08" @default.
• W2076893246 title "Restoration of depressed prostanoid-induced ileal contraction in spontaneously hypertensive rats by dietary fish oil" @default.
• W2076893246 cites W121462954 @default.
• W2076893246 cites W1516334152 @default.
• W2076893246 cites W1775749144 @default.
• W2076893246 cites W1831043359 @default.
• W2076893246 cites W1831301545 @default.
• W2076893246 cites W1889139395 @default.
• W2076893246 cites W1916771372 @default.
• W2076893246 cites W1924898689 @default.
• W2076893246 cites W1933905631 @default.
• W2076893246 cites W1943326237 @default.
• W2076893246 cites W1965836547 @default.
• W2076893246 cites W1971524197 @default.
• W2076893246 cites W1975789875 @default.
• W2076893246 cites W1985490685 @default.
• W2076893246 cites W2000197092 @default.
• W2076893246 cites W2013059922 @default.
• W2076893246 cites W2016287915 @default.
• W2076893246 cites W2030684041 @default.
• W2076893246 cites W2031758133 @default.
• W2076893246 cites W2049377710 @default.
• W2076893246 cites W2051970013 @default.
• W2076893246 cites W2052200307 @default.
• W2076893246 cites W2057411366 @default.
• W2076893246 cites W2060145788 @default.
• W2076893246 cites W2067199548 @default.
• W2076893246 cites W2076295231 @default.
• W2076893246 cites W2081839805 @default.
• W2076893246 cites W2082704648 @default.
• W2076893246 cites W2088061275 @default.
• W2076893246 cites W2096553071 @default.
• W2076893246 cites W2104799917 @default.
• W2076893246 cites W2106592424 @default.
• W2076893246 cites W2106736556 @default.
• W2076893246 cites W2110802793 @default.
• W2076893246 cites W2148863905 @default.
• W2076893246 cites W2154917817 @default.
• W2076893246 cites W2160208015 @default.
• W2076893246 cites W2164071126 @default.
• W2076893246 cites W2166059675 @default.
• W2076893246 cites W2169890226 @default.
• W2076893246 cites W2185757459 @default.
• W2076893246 cites W2200494874 @default.
• W2076893246 cites W2791676076 @default.
• W2076893246 cites W46214796 @default.
• W2076893246 doi "https://doi.org/10.1007/s11745-005-1361-9" @default.
• W2076893246 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15825832" @default.
• W2076893246 hasPublicationYear "2005" @default.
• W2076893246 type Work @default.
• W2076893246 sameAs 2076893246 @default.
• W2076893246 citedByCount "9" @default.
• W2076893246 countsByYear W20768932462012 @default.
• W2076893246 countsByYear W20768932462015 @default.
• W2076893246 countsByYear W20768932462016 @default.
• W2076893246 crossrefType "journal-article" @default.
• W2076893246 hasAuthorship W2076893246A5018026838 @default.
• W2076893246 hasAuthorship W2076893246A5018280281 @default.
• W2076893246 hasAuthorship W2076893246A5043951707 @default.
• W2076893246 hasAuthorship W2076893246A5048846339 @default.
• W2076893246 hasAuthorship W2076893246A5051068014 @default.
• W2076893246 hasAuthorship W2076893246A5087320270 @default.
• W2076893246 hasConcept C126322002 @default.
• W2076893246 hasConcept C134018914 @default.
• W2076893246 hasConcept C163415756 @default.
• W2076893246 hasConcept C181199279 @default.
• W2076893246 hasConcept C185592680 @default.
• W2076893246 hasConcept C19038510 @default.
• W2076893246 hasConcept C2777226302 @default.
• W2076893246 hasConcept C2778078955 @default.
• W2076893246 hasConcept C2778206080 @default.
• W2076893246 hasConcept C2779946292 @default.
• W2076893246 hasConcept C2909208804 @default.
• W2076893246 hasConcept C39133596 @default.
• W2076893246 hasConcept C505870484 @default.
• W2076893246 hasConcept C543025807 @default.
• W2076893246 hasConcept C55493867 @default.
• W2076893246 hasConcept C71924100 @default.
• W2076893246 hasConcept C86803240 @default.
• W2076893246 hasConceptScore W2076893246C126322002 @default.
• W2076893246 hasConceptScore W2076893246C134018914 @default.
• W2076893246 hasConceptScore W2076893246C163415756 @default.
• W2076893246 hasConceptScore W2076893246C181199279 @default.
• W2076893246 hasConceptScore W2076893246C185592680 @default.
• W2076893246 hasConceptScore W2076893246C19038510 @default.
• W2076893246 hasConceptScore W2076893246C2777226302 @default.
• W2076893246 hasConceptScore W2076893246C2778078955 @default.
• W2076893246 hasConceptScore W2076893246C2778206080 @default.
• W2076893246 hasConceptScore W2076893246C2779946292 @default.

• next