FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2076940398> ?p ?o ?g. }

• W2076940398 abstract "Environmental exposures vary by timing, severity, and frequency and may have a number of deleterious effects throughout the life course. The period of in utero development, for example, is one of the most crucial stages of development during which adverse environmental exposures can both alter the growth and development of the fetus as well as lead to aberrant fetal programming, increasing disease risk. During fetal development and beyond, the plethora of exposures, including nutrients, drugs, stress, and trauma, influence health, development, and survival. Recent research in environmental epigenetics has investigated the roles of environmental exposures in influencing epigenetic modes of gene regulation during pregnancy and at various stages of life. Many relatively common environmental exposures, such as cigarette smoking, alcohol consumption, and drug use, may have consequences for the expression and function of non-coding RNA (ncRNA), important post-transcriptional regulators of gene expression. A number of ncRNA have been discovered, including microRNA (miRNA), Piwi-interacting RNA (piRNA), and long non-coding RNA (long ncRNA). The best-characterized species of ncRNA are miRNA, the mature forms of which are ∼22 nucleotides in length and capable of post-transcriptionally regulating target mRNA utilizing mechanisms based largely on the degree of complementarity between miRNA and target mRNA. Because miRNA can still negatively regulate gene expression when imperfectly base-paired with a target mRNA, a single miRNA can have a large number of potential mRNA targets and can regulate many different biological processes critical for health and development. The following review analyzes the current literature detailing links between cigarette smoke exposure and aberrant expression and function of ncRNA, assesses how such alterations may have consequences throughout the life course, and proposes future directions for this intriguing field of research." @default.
• W2076940398 created "2016-06-24" @default.
• W2076940398 creator A5008726967 @default.
• W2076940398 creator A5060278809 @default.
• W2076940398 date "2012-01-01" @default.
• W2076940398 modified "2023-10-16" @default.
• W2076940398 title "Cigarette Smoke Exposure-Associated Alterations to Non-Coding RNA" @default.
• W2076940398 cites W138114664 @default.
• W2076940398 cites W1541826294 @default.
• W2076940398 cites W1548712130 @default.
• W2076940398 cites W1823444227 @default.
• W2076940398 cites W1892653283 @default.
• W2076940398 cites W1920303762 @default.
• W2076940398 cites W1966714489 @default.
• W2076940398 cites W1975437957 @default.
• W2076940398 cites W1976342457 @default.
• W2076940398 cites W1978337436 @default.
• W2076940398 cites W1979954557 @default.
• W2076940398 cites W1980269624 @default.
• W2076940398 cites W1984384441 @default.
• W2076940398 cites W1990654003 @default.
• W2076940398 cites W1992941735 @default.
• W2076940398 cites W1995947881 @default.
• W2076940398 cites W1999478182 @default.
• W2076940398 cites W2000629769 @default.
• W2076940398 cites W2002708668 @default.
• W2076940398 cites W2005445084 @default.
• W2076940398 cites W2007015770 @default.
• W2076940398 cites W2014064723 @default.
• W2076940398 cites W2028444170 @default.
• W2076940398 cites W2035930185 @default.
• W2076940398 cites W2038766179 @default.
• W2076940398 cites W2042673698 @default.
• W2076940398 cites W2044229258 @default.
• W2076940398 cites W2045297101 @default.
• W2076940398 cites W2047988520 @default.
• W2076940398 cites W2049419451 @default.
• W2076940398 cites W2050066317 @default.
• W2076940398 cites W2050256724 @default.
• W2076940398 cites W2065568110 @default.
• W2076940398 cites W2065879615 @default.
• W2076940398 cites W2068847708 @default.
• W2076940398 cites W2070571588 @default.
• W2076940398 cites W2071596792 @default.
• W2076940398 cites W2074106269 @default.
• W2076940398 cites W2076828391 @default.
• W2076940398 cites W2077134893 @default.
• W2076940398 cites W2079205571 @default.
• W2076940398 cites W2079372953 @default.
• W2076940398 cites W2082213106 @default.
• W2076940398 cites W2091217268 @default.
• W2076940398 cites W2091929022 @default.
• W2076940398 cites W2095640847 @default.
• W2076940398 cites W2103611039 @default.
• W2076940398 cites W2106929712 @default.
• W2076940398 cites W2109100311 @default.
• W2076940398 cites W2111217101 @default.
• W2076940398 cites W2117132581 @default.
• W2076940398 cites W2118420574 @default.
• W2076940398 cites W2119489884 @default.
• W2076940398 cites W2120081922 @default.
• W2076940398 cites W2120894058 @default.
• W2076940398 cites W2124293809 @default.
• W2076940398 cites W2124428687 @default.
• W2076940398 cites W2125489084 @default.
• W2076940398 cites W2126140941 @default.
• W2076940398 cites W2132067226 @default.
• W2076940398 cites W2136384445 @default.
• W2076940398 cites W2138664009 @default.
• W2076940398 cites W2139334238 @default.
• W2076940398 cites W2145429652 @default.
• W2076940398 cites W2146642335 @default.
• W2076940398 cites W2148575470 @default.
• W2076940398 cites W2149291473 @default.
• W2076940398 cites W2151922790 @default.
• W2076940398 cites W2153245242 @default.
• W2076940398 cites W2155954232 @default.
• W2076940398 cites W2158006177 @default.
• W2076940398 cites W2160867153 @default.
• W2076940398 cites W2161859153 @default.
• W2076940398 cites W2162552052 @default.
• W2076940398 cites W2165764599 @default.
• W2076940398 cites W2167557255 @default.
• W2076940398 cites W4236615275 @default.
• W2076940398 cites W4236918658 @default.
• W2076940398 cites W4249431887 @default.
• W2076940398 cites W4302423310 @default.
• W2076940398 cites W4302837505 @default.
• W2076940398 doi "https://doi.org/10.3389/fgene.2012.00053" @default.
• W2076940398 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3321413" @default.
• W2076940398 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22509180" @default.
• W2076940398 hasPublicationYear "2012" @default.
• W2076940398 type Work @default.
• W2076940398 sameAs 2076940398 @default.
• W2076940398 citedByCount "35" @default.
• W2076940398 countsByYear W20769403982012 @default.
• W2076940398 countsByYear W20769403982013 @default.
• W2076940398 countsByYear W20769403982014 @default.
• W2076940398 countsByYear W20769403982015 @default.
• W2076940398 countsByYear W20769403982016 @default.

• next