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- W2076959105 abstract "The E-cadherin cell adhesion molecule is associated with cytoplasmic polypeptides, and this association is essential for its cell-binding function. Using isolated adherens junctions of the liver, we purified a 102 kd protein that can associate with E-cadherin (CAP102) and isolated cDNAs encoding this protein. Sequence analysis of the cDNAs revealed that this protein has a similarity to vinculin. L cells not expressing endogenous cadherin express the mRNA for CAP102 but have only a trace amount of CAP102 protein. Introducing exogenous E-cadherin into these cells, however, induced a high expression of CAP102 protein without affecting the amount of its mRNA, suggesting that there is a posttranscriptional regulatory mechanism for this molecule. The same effect was observed by introducing N- or P-cadherin into L cells." @default.
- W2076959105 created "2016-06-24" @default.
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- W2076959105 date "1991-05-01" @default.
- W2076959105 modified "2023-10-12" @default.
- W2076959105 title "The 102 kd cadherin-associated protein: Similarity to vinculin and posttranscriptional regulation of expression" @default.
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- W2076959105 doi "https://doi.org/10.1016/0092-8674(91)90392-c" @default.
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