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- W2076979909 abstract "MOHANDAS et al. (1981) have proposed that mammalian X chromosome inactivation involves segmental methylation of cytosine residues in the DNA at multiple sites along the X chromosome. Using antibodies specific for 5-methylcytosine, we have found no detectable difference in the extent of methylation of the DNA in the two X chromosomes of owl monkey or human females. Thus inactivation (facultative heterochromatization) of the X chromosome is not due to, or associated with, intense DNA methylation comparable to that seen in most constitutive heterochromatin." @default.
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- W2076979909 date "1982-01-01" @default.
- W2076979909 modified "2023-09-25" @default.
- W2076979909 title "Is DNA methylation responsible for mammalian X chromosome inactivation?" @default.
- W2076979909 doi "https://doi.org/10.1159/000131782" @default.
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