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- W2076985013 abstract "Teleocidin, which was isolated from mycelia of Streptomyces, is a potent tumor promoter in mouse skin. The catalytically hydrogenated compound dihydroteleocidin B markedly enhanced malignant cell transformation induced by 3-methylcholanthrene or ultraviolet radiation. Dihydroteleocidin B was at least 100 times more effective in enhancing transformation than 12-O-tetradecanoyl phorbol-13-acetate, the strongest promoter known until now, whereas both promoters showed equal capacities to induce early membrane effects and DNA synthesis." @default.
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- W2076985013 date "1982-04-30" @default.
- W2076985013 modified "2023-09-25" @default.
- W2076985013 title "A new tumor-promoting agent, dihydroteleocidin B, markedly enhances chemically induced malignant cell transformation" @default.
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- W2076985013 doi "https://doi.org/10.1126/science.6280280" @default.
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