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- W2076987145 abstract "16 patients with chronic hepatitis C virus (HCV) infection were treated with a combination of interferon-alpha and ribavirin for 24 weeks in an open study. One patient declined further treatment due to depression after week 16 and did not complete further follow-up. A moderate decline was observed in hemoglobin and an increase in bilirubin level both reversible after discontinuing the treatment. 24 weeks after treatment cessation 9/15 (60%) evaluable patients had complete clearance of HCV-RNA as measured with PCR. HCV genotype did not seem to be correlated with response, but patients with sustained response to treatment had a significantly reduced number of HCV RNA copies/ml serum at treatment start compared with the other patients. These findings support the promising results of this combination therapy noted in other pilot studies." @default.
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- W2076987145 date "1995-01-01" @default.
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- W2076987145 title "Combined Alpha-interferon and Ribavirin Treatment in Chronic Hepatitis C: A Pilot Study" @default.
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- W2076987145 doi "https://doi.org/10.3109/00365549509032725" @default.
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