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• W2076994510 abstract "Novel cisplatin analogs dichloro[4,4'-bis(4,4,4-trifluorobutyl)-2,2'-bipyridine]platinum (1) and fac-tricarbonylchloro[4,4'-bis(4,4,4-trifluorobutyl)-2,2'-bipyridine]rhenium (3) were synthesized and evaluated for their cytotoxicity. While 3 was not cytotoxic, 1 was 14 to 125 times more lethal than cisplatin in breast, prostate, and lung cancer cell lines. Compound 1 was able to induce apoptosis and the presence of the platinum atom was essential to its function as a cytotoxin." @default.
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• W2076994510 date "2006-12-01" @default.
• W2076994510 modified "2023-09-24" @default.
• W2076994510 title "A fluorine containing bipyridine cisplatin analog is more effective than cisplatin at inducing apoptosis in cancer cell lines" @default.
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• W2076994510 doi "https://doi.org/10.1016/j.bmc.2006.08.016" @default.
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