Matches in SemOpenAlex for { <https://semopenalex.org/work/W2077025077> ?p ?o ?g. }
- W2077025077 endingPage "431" @default.
- W2077025077 startingPage "425" @default.
- W2077025077 abstract "Peptide-based vaccines offer several potential advantages over the conventional whole proteins (or whole gene, in the case of genetic immunisation) in terms of purity and a high specificity in eliciting immune responses. However, concerns about toxic adjuvants, which are critical for immunogenicity of synthetic peptides, still remain. Lipopeptides, a form of peptide vaccine, discovered more then a decade ago, are currently under intensive investigation because they can generate comprehensive immune responses, without the use of adjuvants. In this review, we address the past of lipopeptide vaccines, highlight the progress made toward their optimisation, and stress future challenges and issues related to their synthesis, formulation, and delivery. In particular, the recent development of mucosal application of lipopeptide vaccines may present an ideal strategy against many pathogens that infect mucosal surfaces." @default.
- W2077025077 created "2016-06-24" @default.
- W2077025077 creator A5054482428 @default.
- W2077025077 creator A5062310236 @default.
- W2077025077 creator A5091594147 @default.
- W2077025077 date "2002-07-01" @default.
- W2077025077 modified "2023-10-17" @default.
- W2077025077 title "Lipopeptide vaccines—yesterday, today, and tomorrow" @default.
- W2077025077 cites W1504316996 @default.
- W2077025077 cites W1537342340 @default.
- W2077025077 cites W1549285889 @default.
- W2077025077 cites W1562306078 @default.
- W2077025077 cites W1562563051 @default.
- W2077025077 cites W1600700372 @default.
- W2077025077 cites W1610079506 @default.
- W2077025077 cites W1661544713 @default.
- W2077025077 cites W1847185650 @default.
- W2077025077 cites W1952863055 @default.
- W2077025077 cites W1960939533 @default.
- W2077025077 cites W1963895695 @default.
- W2077025077 cites W1972473113 @default.
- W2077025077 cites W1974536984 @default.
- W2077025077 cites W1978765629 @default.
- W2077025077 cites W1984512389 @default.
- W2077025077 cites W1990361264 @default.
- W2077025077 cites W1993250167 @default.
- W2077025077 cites W1993265553 @default.
- W2077025077 cites W1996707986 @default.
- W2077025077 cites W1999426833 @default.
- W2077025077 cites W2003546467 @default.
- W2077025077 cites W2005636903 @default.
- W2077025077 cites W2010667111 @default.
- W2077025077 cites W2011269277 @default.
- W2077025077 cites W2018048760 @default.
- W2077025077 cites W2020437072 @default.
- W2077025077 cites W2035979335 @default.
- W2077025077 cites W2037387436 @default.
- W2077025077 cites W2040044441 @default.
- W2077025077 cites W2044226704 @default.
- W2077025077 cites W2051194884 @default.
- W2077025077 cites W2057581357 @default.
- W2077025077 cites W2060031717 @default.
- W2077025077 cites W2061413166 @default.
- W2077025077 cites W2062784367 @default.
- W2077025077 cites W2064145322 @default.
- W2077025077 cites W2067034588 @default.
- W2077025077 cites W2068290312 @default.
- W2077025077 cites W2069528963 @default.
- W2077025077 cites W2073207520 @default.
- W2077025077 cites W2073699262 @default.
- W2077025077 cites W2073883965 @default.
- W2077025077 cites W2075011082 @default.
- W2077025077 cites W2081145191 @default.
- W2077025077 cites W2084848770 @default.
- W2077025077 cites W2087497136 @default.
- W2077025077 cites W2117534618 @default.
- W2077025077 cites W2125729298 @default.
- W2077025077 cites W2129550844 @default.
- W2077025077 cites W2130435770 @default.
- W2077025077 cites W2131246210 @default.
- W2077025077 cites W2143000004 @default.
- W2077025077 cites W2145584783 @default.
- W2077025077 cites W2147509179 @default.
- W2077025077 cites W2159887295 @default.
- W2077025077 cites W2160520953 @default.
- W2077025077 cites W2171601782 @default.
- W2077025077 cites W2177327503 @default.
- W2077025077 cites W2262757894 @default.
- W2077025077 doi "https://doi.org/10.1016/s1473-3099(02)00318-3" @default.
- W2077025077 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12127354" @default.
- W2077025077 hasPublicationYear "2002" @default.
- W2077025077 type Work @default.
- W2077025077 sameAs 2077025077 @default.
- W2077025077 citedByCount "173" @default.
- W2077025077 countsByYear W20770250772012 @default.
- W2077025077 countsByYear W20770250772013 @default.
- W2077025077 countsByYear W20770250772014 @default.
- W2077025077 countsByYear W20770250772015 @default.
- W2077025077 countsByYear W20770250772016 @default.
- W2077025077 countsByYear W20770250772017 @default.
- W2077025077 countsByYear W20770250772018 @default.
- W2077025077 countsByYear W20770250772019 @default.
- W2077025077 countsByYear W20770250772020 @default.
- W2077025077 countsByYear W20770250772021 @default.
- W2077025077 countsByYear W20770250772023 @default.
- W2077025077 crossrefType "journal-article" @default.
- W2077025077 hasAuthorship W2077025077A5054482428 @default.
- W2077025077 hasAuthorship W2077025077A5062310236 @default.
- W2077025077 hasAuthorship W2077025077A5091594147 @default.
- W2077025077 hasConcept C121332964 @default.
- W2077025077 hasConcept C1276947 @default.
- W2077025077 hasConcept C203014093 @default.
- W2077025077 hasConcept C2777425210 @default.
- W2077025077 hasConcept C2777840570 @default.
- W2077025077 hasConcept C2780868878 @default.
- W2077025077 hasConcept C523546767 @default.
- W2077025077 hasConcept C54355233 @default.
- W2077025077 hasConcept C70721500 @default.