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- W2077051483 abstract "Welcome to this special issue of PPAR Research, PPARs: A Double-Edged Sword in Cancer Therapy. Peroxisome Proliferator-Activated Receptors (PPARs) are a family of pleiotropic transcription factors that play central roles in cell metabolism and regulation of inflammation. Cancer is thought to be the uncontrolled clonal evolution and expansion of a mutated cell [1]. What is the connection between PPARs and cancer? The theme of this special issue reflects the impressive confluence of two originally separate streams of investigation: PPARs and cancer research. Despite the multitude of points of intersection between PPARs and neoplasia, and associated unresolved paradoxes, the link between PPARs and tumors is not yet widely appreciated among specialists in either field. However, over the past years, investigators who cross these fields have unearthed a myriad of remarkable connections." @default.
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- W2077051483 date "2008-01-01" @default.
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- W2077051483 title "PPARs: A Double-Edged Sword in Cancer Therapy?" @default.
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- W2077051483 doi "https://doi.org/10.1155/2008/350351" @default.
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