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- W2077112282 abstract "The typical toxidrome in organophosphate (OP) poisoning comprises of the Salivation, Lacrimation, Urination, Defecation, Gastric cramps, Emesis (SLUDGE) symptoms. However, several other manifestations are described. We review the spectrum of symptoms and signs in OP poisoning as well as the different approaches to clinical features in these patients.Articles were obtained by electronic search of PubMed(®) between 1966 and April 2014 using the search terms organophosphorus compounds or phosphoric acid esters AND poison or poisoning AND manifestations.Of the 5026 articles on OP poisoning, 2584 articles pertained to human poisoning; 452 articles focusing on clinical manifestations in human OP poisoning were retrieved for detailed evaluation. In addition to the traditional approach of symptoms and signs of OP poisoning as peripheral (muscarinic, nicotinic) and central nervous system receptor stimulation, symptoms were alternatively approached using a time-based classification. In this, symptom onset was categorized as acute (within 24-h), delayed (24-h to 2-week) or late (beyond 2-week). Although most symptoms occur with minutes or hours following acute exposure, delayed onset symptoms occurring after a period of minimal or mild symptoms, may impact treatment and timing of the discharge following acute exposure. Symptoms and signs were also viewed as an organ specific as cardiovascular, respiratory or neurological manifestations. An organ specific approach enables focused management of individual organ dysfunction that may vary with different OP compounds.Different approaches to the symptoms and signs in OP poisoning may better our understanding of the underlying mechanism that in turn may assist with the management of acutely poisoned patients." @default.
- W2077112282 created "2016-06-24" @default.
- W2077112282 creator A5049721158 @default.
- W2077112282 creator A5079909351 @default.
- W2077112282 creator A5083319191 @default.
- W2077112282 date "2014-01-01" @default.
- W2077112282 modified "2023-10-13" @default.
- W2077112282 title "Clinical features of organophosphate poisoning: A review of different classification systems and approaches" @default.
- W2077112282 cites W149195305 @default.
- W2077112282 cites W1513183398 @default.
- W2077112282 cites W1555390786 @default.
- W2077112282 cites W156768682 @default.
- W2077112282 cites W1571110680 @default.
- W2077112282 cites W1593402947 @default.
- W2077112282 cites W166984380 @default.
- W2077112282 cites W177720256 @default.
- W2077112282 cites W1963711362 @default.
- W2077112282 cites W1966714270 @default.
- W2077112282 cites W1970005804 @default.
- W2077112282 cites W1977247248 @default.
- W2077112282 cites W1978262774 @default.
- W2077112282 cites W1980738372 @default.
- W2077112282 cites W1982626773 @default.
- W2077112282 cites W1989905989 @default.
- W2077112282 cites W1992085446 @default.
- W2077112282 cites W1994445881 @default.
- W2077112282 cites W1999102413 @default.
- W2077112282 cites W1999417675 @default.
- W2077112282 cites W2003510586 @default.
- W2077112282 cites W2004313775 @default.
- W2077112282 cites W2004868091 @default.
- W2077112282 cites W2005004090 @default.
- W2077112282 cites W2008167175 @default.
- W2077112282 cites W2008407837 @default.
- W2077112282 cites W2008507262 @default.
- W2077112282 cites W2011859992 @default.
- W2077112282 cites W2016943197 @default.
- W2077112282 cites W2020663409 @default.
- W2077112282 cites W2022587369 @default.
- W2077112282 cites W2030115611 @default.
- W2077112282 cites W2032717400 @default.
- W2077112282 cites W2034002826 @default.
- W2077112282 cites W2040402393 @default.
- W2077112282 cites W2043032451 @default.
- W2077112282 cites W2043539293 @default.
- W2077112282 cites W2057125934 @default.
- W2077112282 cites W2058203830 @default.
- W2077112282 cites W2058482253 @default.
- W2077112282 cites W2062699083 @default.
- W2077112282 cites W2069139535 @default.
- W2077112282 cites W2070450103 @default.
- W2077112282 cites W2072494371 @default.
- W2077112282 cites W2073641872 @default.
- W2077112282 cites W2074454978 @default.
- W2077112282 cites W2074528910 @default.
- W2077112282 cites W2076916359 @default.
- W2077112282 cites W2078362738 @default.
- W2077112282 cites W2079926564 @default.
- W2077112282 cites W2080714150 @default.
- W2077112282 cites W2082174689 @default.
- W2077112282 cites W2082203299 @default.
- W2077112282 cites W2083536424 @default.
- W2077112282 cites W2083617069 @default.
- W2077112282 cites W2084179179 @default.
- W2077112282 cites W2084930764 @default.
- W2077112282 cites W2089163487 @default.
- W2077112282 cites W2093294282 @default.
- W2077112282 cites W2094249923 @default.
- W2077112282 cites W2094796024 @default.
- W2077112282 cites W2099045381 @default.
- W2077112282 cites W2099455401 @default.
- W2077112282 cites W2103509757 @default.
- W2077112282 cites W2105391780 @default.
- W2077112282 cites W2107952228 @default.
- W2077112282 cites W2111534108 @default.
- W2077112282 cites W2115916063 @default.
- W2077112282 cites W2117567134 @default.
- W2077112282 cites W2118706753 @default.
- W2077112282 cites W2129165421 @default.
- W2077112282 cites W2132397671 @default.
- W2077112282 cites W2137696449 @default.
- W2077112282 cites W2139666704 @default.
- W2077112282 cites W2140989648 @default.
- W2077112282 cites W2141435131 @default.
- W2077112282 cites W2143486809 @default.
- W2077112282 cites W2143851225 @default.
- W2077112282 cites W2147955515 @default.
- W2077112282 cites W2149925367 @default.
- W2077112282 cites W2153909774 @default.
- W2077112282 cites W2157787692 @default.
- W2077112282 cites W2161236690 @default.
- W2077112282 cites W2161244484 @default.
- W2077112282 cites W2162431496 @default.
- W2077112282 cites W2164545418 @default.
- W2077112282 cites W2167835023 @default.
- W2077112282 cites W2168471116 @default.
- W2077112282 cites W2170690877 @default.
- W2077112282 cites W2170909907 @default.