Matches in SemOpenAlex for { <https://semopenalex.org/work/W2077132336> ?p ?o ?g. }
- W2077132336 endingPage "782" @default.
- W2077132336 startingPage "774" @default.
- W2077132336 abstract "The mechanisms underlying the teratogen-induced apoptotic process leading to anomaly formation are not as yet understood. Therefore, we tried to evaluate possible changes in the expression of molecules regulating the apoptotic process induced in the embryo and placenta by exposure to cyclophosphamide (CP). Exposure to CP resulted in clear growth retardation that was accompanied by a time-dependent increase in cellular damage and an appearance of apoptotic cells in the embryonic brain and limbs as well as a decrease in cell proliferation. Western blot analysis demonstrated an increase in the level of Bax and a decrease in the expression of the p65 subunit of NF-kappaB and IkappaB alpha in the embryo and placenta. Immunohistochemical analysis localized cells expressing those molecules to the areas that exhibited CP-induced cellular damage, while in the placenta they were revealed mainly in the luminal and glandular epithelium. Our results suggest a possible involvement of Bax, p65 and IkappaB alpha in the response of the embryo and the placenta to teratogenic insults." @default.
- W2077132336 created "2016-06-24" @default.
- W2077132336 creator A5000962180 @default.
- W2077132336 creator A5019498163 @default.
- W2077132336 creator A5024627314 @default.
- W2077132336 creator A5025643642 @default.
- W2077132336 creator A5026532009 @default.
- W2077132336 creator A5056670978 @default.
- W2077132336 creator A5073219159 @default.
- W2077132336 creator A5075666938 @default.
- W2077132336 date "2006-11-01" @default.
- W2077132336 modified "2023-09-26" @default.
- W2077132336 title "Expression of apoptosis-associated molecules in the fetoplacental unit of cyclophosphamide-treated mice" @default.
- W2077132336 cites W107210068 @default.
- W2077132336 cites W1578880263 @default.
- W2077132336 cites W1888783223 @default.
- W2077132336 cites W1983237485 @default.
- W2077132336 cites W1986916123 @default.
- W2077132336 cites W1988124690 @default.
- W2077132336 cites W2003185547 @default.
- W2077132336 cites W2003933151 @default.
- W2077132336 cites W2008948379 @default.
- W2077132336 cites W2011007912 @default.
- W2077132336 cites W2018236695 @default.
- W2077132336 cites W2032531389 @default.
- W2077132336 cites W2039355845 @default.
- W2077132336 cites W2040967530 @default.
- W2077132336 cites W2041760692 @default.
- W2077132336 cites W2043028610 @default.
- W2077132336 cites W2045872949 @default.
- W2077132336 cites W2047131566 @default.
- W2077132336 cites W2056326139 @default.
- W2077132336 cites W2069778851 @default.
- W2077132336 cites W2070764921 @default.
- W2077132336 cites W2072252062 @default.
- W2077132336 cites W2080057746 @default.
- W2077132336 cites W2080727274 @default.
- W2077132336 cites W2087489585 @default.
- W2077132336 cites W2087877138 @default.
- W2077132336 cites W2088381214 @default.
- W2077132336 cites W2091689368 @default.
- W2077132336 cites W2100089767 @default.
- W2077132336 cites W2109992434 @default.
- W2077132336 cites W2118558106 @default.
- W2077132336 cites W2119044641 @default.
- W2077132336 cites W2128525107 @default.
- W2077132336 cites W2130866079 @default.
- W2077132336 cites W2136790318 @default.
- W2077132336 cites W2141205853 @default.
- W2077132336 cites W2142840808 @default.
- W2077132336 cites W2155516654 @default.
- W2077132336 cites W2170054202 @default.
- W2077132336 cites W2202279532 @default.
- W2077132336 cites W1594038390 @default.
- W2077132336 doi "https://doi.org/10.1016/j.reprotox.2006.07.009" @default.
- W2077132336 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16952439" @default.
- W2077132336 hasPublicationYear "2006" @default.
- W2077132336 type Work @default.
- W2077132336 sameAs 2077132336 @default.
- W2077132336 citedByCount "9" @default.
- W2077132336 countsByYear W20771323362013 @default.
- W2077132336 countsByYear W20771323362015 @default.
- W2077132336 countsByYear W20771323362023 @default.
- W2077132336 crossrefType "journal-article" @default.
- W2077132336 hasAuthorship W2077132336A5000962180 @default.
- W2077132336 hasAuthorship W2077132336A5019498163 @default.
- W2077132336 hasAuthorship W2077132336A5024627314 @default.
- W2077132336 hasAuthorship W2077132336A5025643642 @default.
- W2077132336 hasAuthorship W2077132336A5026532009 @default.
- W2077132336 hasAuthorship W2077132336A5056670978 @default.
- W2077132336 hasAuthorship W2077132336A5073219159 @default.
- W2077132336 hasAuthorship W2077132336A5075666938 @default.
- W2077132336 hasConcept C104317684 @default.
- W2077132336 hasConcept C145103041 @default.
- W2077132336 hasConcept C16685009 @default.
- W2077132336 hasConcept C172680121 @default.
- W2077132336 hasConcept C190283241 @default.
- W2077132336 hasConcept C196843134 @default.
- W2077132336 hasConcept C203014093 @default.
- W2077132336 hasConcept C204232928 @default.
- W2077132336 hasConcept C2776415932 @default.
- W2077132336 hasConcept C2776953305 @default.
- W2077132336 hasConcept C2779234561 @default.
- W2077132336 hasConcept C31573885 @default.
- W2077132336 hasConcept C54355233 @default.
- W2077132336 hasConcept C55493867 @default.
- W2077132336 hasConcept C71924100 @default.
- W2077132336 hasConcept C86803240 @default.
- W2077132336 hasConcept C95444343 @default.
- W2077132336 hasConceptScore W2077132336C104317684 @default.
- W2077132336 hasConceptScore W2077132336C145103041 @default.
- W2077132336 hasConceptScore W2077132336C16685009 @default.
- W2077132336 hasConceptScore W2077132336C172680121 @default.
- W2077132336 hasConceptScore W2077132336C190283241 @default.
- W2077132336 hasConceptScore W2077132336C196843134 @default.
- W2077132336 hasConceptScore W2077132336C203014093 @default.
- W2077132336 hasConceptScore W2077132336C204232928 @default.
- W2077132336 hasConceptScore W2077132336C2776415932 @default.