Matches in SemOpenAlex for { <https://semopenalex.org/work/W2077162013> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2077162013 endingPage "530" @default.
- W2077162013 startingPage "517" @default.
- W2077162013 abstract "In view of the recent finding that prostaglandin D2 is stereospecifically converted to 9α,11β-prostaglandin F2, an isomer of prostaglandin F2α, a highly specific and sensitive radioimmunoassay for 9α,11β-prostaglandin F2 was developed and applied to determine the content of this prostaglandin in various rat tissues. Antisera against 9α-11β-prostaglandin F2 were raised in rabbits immunized with the bovine serum albumin conjugate, and [3H]9α,11β-prostaglandin F2 was enzymatically prepared from [3H]prostaglandin D2. The assay detected 9α,11β-prostaglandin F2 over the range of 20 pg to 1 ng, and the antiserum showed less than 0.04% cross-section with prostaglandin F2α, prostaglandin F2β and 9β,11β-prostaglandin F2. To avoid postmortem changes, tissues were frozen in liquid nitrogen immediately after removal. The basal level of 9α,11β-prostaglandin F2 was hardly detectable in various tissues of the rat examined, including spleen, lung, liver and brain; although it was found to be 0.31 ± 0.06 ng/g wet weight in the small intestine. During convulsion induced by pentylenetetrazole, enormous amounts of prostaglandin D2 (ca. 180 ng/g wet weight) and prostaglandin F2α (ca. 70 ng/g) were produced in the brain; however, 9α,11β-prostaglandin F2 was detected neither there nor in the blood. This result demonstrates that the conversion to 9α,11β-prostaglandin F2 is a minor pathway, if one at all, of prostaglandin D2 metabolism in the rat brain." @default.
- W2077162013 created "2016-06-24" @default.
- W2077162013 creator A5005778977 @default.
- W2077162013 creator A5012590056 @default.
- W2077162013 creator A5021039738 @default.
- W2077162013 creator A5026027669 @default.
- W2077162013 creator A5064125582 @default.
- W2077162013 creator A5064701201 @default.
- W2077162013 creator A5069082137 @default.
- W2077162013 creator A5083644276 @default.
- W2077162013 date "1987-04-01" @default.
- W2077162013 modified "2023-10-12" @default.
- W2077162013 title "Determination of 9α,11β-prostaglandin F2 by stereospecific antibody in various rat tissues" @default.
- W2077162013 cites W1496876439 @default.
- W2077162013 cites W1519633029 @default.
- W2077162013 cites W1528202423 @default.
- W2077162013 cites W1547971522 @default.
- W2077162013 cites W1554005852 @default.
- W2077162013 cites W1601584877 @default.
- W2077162013 cites W1767476647 @default.
- W2077162013 cites W1968196637 @default.
- W2077162013 cites W1971750823 @default.
- W2077162013 cites W1973446102 @default.
- W2077162013 cites W1987197854 @default.
- W2077162013 cites W1989313920 @default.
- W2077162013 cites W1994735101 @default.
- W2077162013 cites W2013190602 @default.
- W2077162013 cites W2027971789 @default.
- W2077162013 cites W2050964427 @default.
- W2077162013 cites W2052091668 @default.
- W2077162013 cites W2070095270 @default.
- W2077162013 cites W2073627659 @default.
- W2077162013 cites W2086727474 @default.
- W2077162013 doi "https://doi.org/10.1016/0090-6980(87)90275-9" @default.
- W2077162013 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3474704" @default.
- W2077162013 hasPublicationYear "1987" @default.
- W2077162013 type Work @default.
- W2077162013 sameAs 2077162013 @default.
- W2077162013 citedByCount "13" @default.
- W2077162013 countsByYear W20771620132012 @default.
- W2077162013 crossrefType "journal-article" @default.
- W2077162013 hasAuthorship W2077162013A5005778977 @default.
- W2077162013 hasAuthorship W2077162013A5012590056 @default.
- W2077162013 hasAuthorship W2077162013A5021039738 @default.
- W2077162013 hasAuthorship W2077162013A5026027669 @default.
- W2077162013 hasAuthorship W2077162013A5064125582 @default.
- W2077162013 hasAuthorship W2077162013A5064701201 @default.
- W2077162013 hasAuthorship W2077162013A5069082137 @default.
- W2077162013 hasAuthorship W2077162013A5083644276 @default.
- W2077162013 hasConcept C126322002 @default.
- W2077162013 hasConcept C134018914 @default.
- W2077162013 hasConcept C159654299 @default.
- W2077162013 hasConcept C176685330 @default.
- W2077162013 hasConcept C185592680 @default.
- W2077162013 hasConcept C203014093 @default.
- W2077162013 hasConcept C2777198256 @default.
- W2077162013 hasConcept C2777361909 @default.
- W2077162013 hasConcept C2780664492 @default.
- W2077162013 hasConcept C71924100 @default.
- W2077162013 hasConcept C86803240 @default.
- W2077162013 hasConcept C91523082 @default.
- W2077162013 hasConceptScore W2077162013C126322002 @default.
- W2077162013 hasConceptScore W2077162013C134018914 @default.
- W2077162013 hasConceptScore W2077162013C159654299 @default.
- W2077162013 hasConceptScore W2077162013C176685330 @default.
- W2077162013 hasConceptScore W2077162013C185592680 @default.
- W2077162013 hasConceptScore W2077162013C203014093 @default.
- W2077162013 hasConceptScore W2077162013C2777198256 @default.
- W2077162013 hasConceptScore W2077162013C2777361909 @default.
- W2077162013 hasConceptScore W2077162013C2780664492 @default.
- W2077162013 hasConceptScore W2077162013C71924100 @default.
- W2077162013 hasConceptScore W2077162013C86803240 @default.
- W2077162013 hasConceptScore W2077162013C91523082 @default.
- W2077162013 hasIssue "4" @default.
- W2077162013 hasLocation W20771620131 @default.
- W2077162013 hasLocation W20771620132 @default.
- W2077162013 hasOpenAccess W2077162013 @default.
- W2077162013 hasPrimaryLocation W20771620131 @default.
- W2077162013 hasRelatedWork W10567745 @default.
- W2077162013 hasRelatedWork W1982640511 @default.
- W2077162013 hasRelatedWork W1988343102 @default.
- W2077162013 hasRelatedWork W1995083701 @default.
- W2077162013 hasRelatedWork W2016034363 @default.
- W2077162013 hasRelatedWork W2043105234 @default.
- W2077162013 hasRelatedWork W2056100207 @default.
- W2077162013 hasRelatedWork W2059568869 @default.
- W2077162013 hasRelatedWork W2159598174 @default.
- W2077162013 hasRelatedWork W2331460308 @default.
- W2077162013 hasVolume "33" @default.
- W2077162013 isParatext "false" @default.
- W2077162013 isRetracted "false" @default.
- W2077162013 magId "2077162013" @default.
- W2077162013 workType "article" @default.