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• W2077175096 endingPage "1721" @default.
• W2077175096 startingPage "1711" @default.
• W2077175096 abstract "Candida endophthalmitis is a sight-threatening manifestation of disseminated candidiasis. The occurrence of endogenous candida endophthalmitis in patients with candidemia has ranged from 0–45% in the published literature. In critically ill patients, it has even been associated with increased mortality. In recent years, use of newer antifungal therapies for invasive candidiasis has increased given the rise in infections with non-albicans species of Candida. To identify current practices of the management of endogenous candida endophthalmitis and relevant antifungal drug research in this disease state, we conducted a MEDLINE search (1967–2006) and bibliographic search of the English-language literature. Treatments for candida endophthalmitis have not been evaluated through well-designed, well-powered clinical trials. Data have mainly been presented in case reports, case series, animal studies, pharmacokinetic studies, and as small subsets of larger trials. Traditional systemic therapies have been amphotericin B with or without flucytosine or fluconazole. Cure rates with antifungal drugs alone appear to be much higher in patients with chorioretinitis than in endophthalmitis with vitreal involvement. Pars plana vitrectomy with or without intravitreal amphotericin B injections has been advocated particularly for patients with moderate-to-severe vitritis and substantial vision loss. Information on new antifungal agents for endophthalmitis is limited, despite increasing use in patients with candidemia. Voriconazole may be a particularly attractive agent to consider for infections with fluconazole-resistant, voriconazole-susceptible strains. The current patchwork of animal studies and small patient reports provide clinicians with some insight into the role of newer agents in the treatment of candida endophthalmitis. In general, it appears that chorioretinitis infections can be more readily cured with most systemic antifungal agents, whereas more aggressive treatment, often including vitrectomy with or without intravitreal antifungal administration, is needed for patients with endophthalmitis with vitritis." @default.
• W2077175096 created "2016-06-24" @default.
• W2077175096 creator A5044149627 @default.
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• W2077175096 date "2007-12-01" @default.
• W2077175096 modified "2023-10-18" @default.
• W2077175096 title "Candida Endophthalmitis: Focus on Current and Future Antifungal Treatment Options" @default.
• W2077175096 cites W16002870 @default.
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• W2077175096 cites W1968527595 @default.
• W2077175096 cites W1969237845 @default.
• W2077175096 cites W1972832101 @default.
• W2077175096 cites W1979584213 @default.
• W2077175096 cites W1979686807 @default.
• W2077175096 cites W1982228166 @default.
• W2077175096 cites W1987292873 @default.
• W2077175096 cites W1993685063 @default.
• W2077175096 cites W2003661565 @default.
• W2077175096 cites W2005212170 @default.
• W2077175096 cites W2005815856 @default.
• W2077175096 cites W2006109942 @default.
• W2077175096 cites W2014098784 @default.
• W2077175096 cites W2014449502 @default.
• W2077175096 cites W2022030316 @default.
• W2077175096 cites W2027460001 @default.
• W2077175096 cites W2031936290 @default.
• W2077175096 cites W2031984989 @default.
• W2077175096 cites W2035000924 @default.
• W2077175096 cites W2038285210 @default.
• W2077175096 cites W2039034599 @default.
• W2077175096 cites W2039386846 @default.
• W2077175096 cites W2047846081 @default.
• W2077175096 cites W2052836877 @default.
• W2077175096 cites W2058176999 @default.
• W2077175096 cites W2059500365 @default.
• W2077175096 cites W2062022402 @default.
• W2077175096 cites W2062329228 @default.
• W2077175096 cites W2069196782 @default.
• W2077175096 cites W2083654319 @default.
• W2077175096 cites W2086430789 @default.
• W2077175096 cites W2089609732 @default.
• W2077175096 cites W2097784274 @default.
• W2077175096 cites W2098256719 @default.
• W2077175096 cites W2101441298 @default.
• W2077175096 cites W2103288314 @default.
• W2077175096 cites W2105413309 @default.
• W2077175096 cites W2105978586 @default.
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• W2077175096 cites W2122092670 @default.
• W2077175096 cites W2123787514 @default.
• W2077175096 cites W2124127923 @default.
• W2077175096 cites W2129133551 @default.
• W2077175096 cites W2133039915 @default.
• W2077175096 cites W2135187530 @default.
• W2077175096 cites W2135303569 @default.
• W2077175096 cites W2135577396 @default.
• W2077175096 cites W2136148468 @default.
• W2077175096 cites W2136377130 @default.
• W2077175096 cites W2143010296 @default.
• W2077175096 cites W2144495358 @default.
• W2077175096 cites W2152107402 @default.
• W2077175096 cites W2158530375 @default.
• W2077175096 cites W2159651541 @default.
• W2077175096 cites W2162594426 @default.
• W2077175096 cites W2167143090 @default.
• W2077175096 cites W2264646809 @default.
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• W2077175096 cites W4290127579 @default.
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• W2077175096 doi "https://doi.org/10.1592/phco.27.12.1711" @default.
• W2077175096 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18041891" @default.
• W2077175096 hasPublicationYear "2007" @default.
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