FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2077180641> ?p ?o ?g. }

• W2077180641 endingPage "279" @default.
• W2077180641 startingPage "271" @default.
• W2077180641 abstract "Small-cell lung cancer (SCLC) accounts for almost 15% of lung carcinomas. Chemotherapy is the cornerstone of treatment of patients with SCLC. In limited disease, median survival is about 12-20 months, with no more than 6%-12% of patients surviving beyond 5 years. In extensive disease, median survival is 7-12 months, with < 5% of patients living beyond 2 years and a 5-year survival rate of just 2%. Several therapeutic approaches have been used in an attempt to improve the outcome of SCLC. Among these, a better understanding of tumor biology and the subsequent development of novel therapeutic strategies have been identified as a possible approach for increasing the survival rate of patients with SCLC. Several targeted agents have been introduced into clinical trials in SCLC, and a few phase III studies, including matrix metalloproteinase inhibitors, thalidomide, and vaccines, have already produced definitive results. Currently, negative results are more commonly reported than positive ones. However, this first generation of clinical trials represents only the beginning of clinical research in this field. To date, no targeted therapy has been approved for use in the treatment of patients with SCLC. Nevertheless, clinical research in this field is still in progress considering that several new targeted agents, such as antiangiogenic agents and mammalian target of rapamycin inhibitors, offer a promise of improved outcomes. This review will focus on the reported results and the future development of the main novel biologic agents for the treatment of patients with SCLC." @default.
• W2077180641 created "2016-06-24" @default.
• W2077180641 creator A5001716875 @default.
• W2077180641 creator A5029922900 @default.
• W2077180641 creator A5032078755 @default.
• W2077180641 creator A5045384053 @default.
• W2077180641 creator A5062527153 @default.
• W2077180641 creator A5067059440 @default.
• W2077180641 creator A5086894884 @default.
• W2077180641 date "2008-09-01" @default.
• W2077180641 modified "2023-10-07" @default.
• W2077180641 title "New Targeted Therapies and Small-Cell Lung Cancer" @default.
• W2077180641 cites W1570233631 @default.
• W2077180641 cites W1752312133 @default.
• W2077180641 cites W1932169383 @default.
• W2077180641 cites W1966706097 @default.
• W2077180641 cites W1973478663 @default.
• W2077180641 cites W1978832223 @default.
• W2077180641 cites W1987194369 @default.
• W2077180641 cites W2003322206 @default.
• W2077180641 cites W2018625819 @default.
• W2077180641 cites W2023389550 @default.
• W2077180641 cites W2026516286 @default.
• W2077180641 cites W2036622300 @default.
• W2077180641 cites W2038110873 @default.
• W2077180641 cites W2038596108 @default.
• W2077180641 cites W2040506871 @default.
• W2077180641 cites W2043103956 @default.
• W2077180641 cites W2052698492 @default.
• W2077180641 cites W2053301922 @default.
• W2077180641 cites W2055789362 @default.
• W2077180641 cites W2058237771 @default.
• W2077180641 cites W2073124245 @default.
• W2077180641 cites W2079713246 @default.
• W2077180641 cites W2082123847 @default.
• W2077180641 cites W2083845012 @default.
• W2077180641 cites W2102598497 @default.
• W2077180641 cites W2108348820 @default.
• W2077180641 cites W2110530327 @default.
• W2077180641 cites W2113214957 @default.
• W2077180641 cites W2124473529 @default.
• W2077180641 cites W2124541554 @default.
• W2077180641 cites W2129527916 @default.
• W2077180641 cites W2129638180 @default.
• W2077180641 cites W2136537241 @default.
• W2077180641 cites W2138683149 @default.
• W2077180641 cites W2147352197 @default.
• W2077180641 cites W2151190428 @default.
• W2077180641 cites W2152583644 @default.
• W2077180641 cites W2156307964 @default.
• W2077180641 cites W2161125717 @default.
• W2077180641 cites W2165132221 @default.
• W2077180641 cites W2171342364 @default.
• W2077180641 cites W2171722798 @default.
• W2077180641 cites W2271351171 @default.
• W2077180641 cites W2323020638 @default.
• W2077180641 cites W2913381773 @default.
• W2077180641 doi "https://doi.org/10.3816/clc.2008.n.042" @default.
• W2077180641 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18824449" @default.
• W2077180641 hasPublicationYear "2008" @default.
• W2077180641 type Work @default.
• W2077180641 sameAs 2077180641 @default.
• W2077180641 citedByCount "37" @default.
• W2077180641 countsByYear W20771806412012 @default.
• W2077180641 countsByYear W20771806412013 @default.
• W2077180641 countsByYear W20771806412014 @default.
• W2077180641 countsByYear W20771806412015 @default.
• W2077180641 countsByYear W20771806412016 @default.
• W2077180641 countsByYear W20771806412017 @default.
• W2077180641 countsByYear W20771806412019 @default.
• W2077180641 countsByYear W20771806412020 @default.
• W2077180641 countsByYear W20771806412021 @default.
• W2077180641 countsByYear W20771806412023 @default.
• W2077180641 crossrefType "journal-article" @default.
• W2077180641 hasAuthorship W2077180641A5001716875 @default.
• W2077180641 hasAuthorship W2077180641A5029922900 @default.
• W2077180641 hasAuthorship W2077180641A5032078755 @default.
• W2077180641 hasAuthorship W2077180641A5045384053 @default.
• W2077180641 hasAuthorship W2077180641A5062527153 @default.
• W2077180641 hasAuthorship W2077180641A5067059440 @default.
• W2077180641 hasAuthorship W2077180641A5086894884 @default.
• W2077180641 hasConcept C121608353 @default.
• W2077180641 hasConcept C126322002 @default.
• W2077180641 hasConcept C143998085 @default.
• W2077180641 hasConcept C2776256026 @default.
• W2077180641 hasConcept C2776364478 @default.
• W2077180641 hasConcept C2776694085 @default.
• W2077180641 hasConcept C2779134260 @default.
• W2077180641 hasConcept C2779609412 @default.
• W2077180641 hasConcept C2781230642 @default.
• W2077180641 hasConcept C535046627 @default.
• W2077180641 hasConcept C71924100 @default.
• W2077180641 hasConceptScore W2077180641C121608353 @default.
• W2077180641 hasConceptScore W2077180641C126322002 @default.
• W2077180641 hasConceptScore W2077180641C143998085 @default.
• W2077180641 hasConceptScore W2077180641C2776256026 @default.
• W2077180641 hasConceptScore W2077180641C2776364478 @default.
• W2077180641 hasConceptScore W2077180641C2776694085 @default.

• next