FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2077185818> ?p ?o ?g. }

• W2077185818 endingPage "220" @default.
• W2077185818 startingPage "209" @default.
• W2077185818 abstract "Sympathetic innervation of lymphoid tissues is localized to specific tissue compartments, but little is known of the “factors” that are important in establishing this pattern during development. Numerous studies have shown interactions of nerve growth factor (NGF) with the immune system, which may include modulation of immune innervation. We previously have shown that NGF transgenic mice, which overexpress NGF in skin and not immune tissues, have a dramatic hyperinnervation of splenic marginal zone and peripheral lymph node medulla and capsule. The purpose of the current studies was to determine if the presence of elevated NGF would alter immune system development and the process of sympathetic ingrowth. The results show that the splenic innervation in NGF transgenics gradually diverged from controls during the first two postnatal weeks, with the greatest change occurring between postnatal days 13 and 16 when the splenic organization was reaching the adult pattern. In contrast, the peripheral lymph nodes were hyperinnervated at an earlier age. Mesenteric lymph nodes never diverged from the normal pattern. NGF levels in transgenic spleen were much higher than controls at postnatal days 1 and 2, when little innervation was present, and declined as the tissue matured, possibly because of NGF uptake by the ingrowing sympathetic fibers. This suggests that immune tissues are capable of concentrating NGF, which in turn may modulate the level of innervation by the sympathetic nervous system." @default.
• W2077185818 created "2016-06-24" @default.
• W2077185818 creator A5029386905 @default.
• W2077185818 creator A5033489455 @default.
• W2077185818 creator A5069967869 @default.
• W2077185818 creator A5070181972 @default.
• W2077185818 date "1998-01-01" @default.
• W2077185818 modified "2023-10-15" @default.
• W2077185818 title "Development of Immune Hyperinnervation in NGF-Transgenic Mice" @default.
• W2077185818 cites W130624342 @default.
• W2077185818 cites W1538074026 @default.
• W2077185818 cites W1584113679 @default.
• W2077185818 cites W1954548044 @default.
• W2077185818 cites W1971029409 @default.
• W2077185818 cites W1977772732 @default.
• W2077185818 cites W1979918788 @default.
• W2077185818 cites W1982068669 @default.
• W2077185818 cites W1983441282 @default.
• W2077185818 cites W1994993130 @default.
• W2077185818 cites W2001837444 @default.
• W2077185818 cites W2003681769 @default.
• W2077185818 cites W2004179558 @default.
• W2077185818 cites W2004388116 @default.
• W2077185818 cites W2005270029 @default.
• W2077185818 cites W2006271972 @default.
• W2077185818 cites W2013460866 @default.
• W2077185818 cites W2017203343 @default.
• W2077185818 cites W2018125085 @default.
• W2077185818 cites W2029869612 @default.
• W2077185818 cites W2034531268 @default.
• W2077185818 cites W2034705701 @default.
• W2077185818 cites W2035976585 @default.
• W2077185818 cites W2035976682 @default.
• W2077185818 cites W2036562186 @default.
• W2077185818 cites W2037975216 @default.
• W2077185818 cites W2041596843 @default.
• W2077185818 cites W2044840652 @default.
• W2077185818 cites W2051453643 @default.
• W2077185818 cites W2051600135 @default.
• W2077185818 cites W2058650902 @default.
• W2077185818 cites W2060265716 @default.
• W2077185818 cites W2060942917 @default.
• W2077185818 cites W2063695629 @default.
• W2077185818 cites W2064820956 @default.
• W2077185818 cites W2065197413 @default.
• W2077185818 cites W2067373118 @default.
• W2077185818 cites W2068892122 @default.
• W2077185818 cites W2076742437 @default.
• W2077185818 cites W2080852683 @default.
• W2077185818 cites W2087075076 @default.
• W2077185818 cites W2088137004 @default.
• W2077185818 cites W2088969302 @default.
• W2077185818 cites W2095351701 @default.
• W2077185818 cites W2096649095 @default.
• W2077185818 cites W2105250650 @default.
• W2077185818 cites W2109748889 @default.
• W2077185818 cites W2149900710 @default.
• W2077185818 cites W2165388753 @default.
• W2077185818 cites W3105898142 @default.
• W2077185818 cites W46103342 @default.
• W2077185818 doi "https://doi.org/10.1006/exnr.1997.6711" @default.
• W2077185818 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9454630" @default.
• W2077185818 hasPublicationYear "1998" @default.
• W2077185818 type Work @default.
• W2077185818 sameAs 2077185818 @default.
• W2077185818 citedByCount "11" @default.
• W2077185818 countsByYear W20771858182013 @default.
• W2077185818 countsByYear W20771858182022 @default.
• W2077185818 crossrefType "journal-article" @default.
• W2077185818 hasAuthorship W2077185818A5029386905 @default.
• W2077185818 hasAuthorship W2077185818A5033489455 @default.
• W2077185818 hasAuthorship W2077185818A5069967869 @default.
• W2077185818 hasAuthorship W2077185818A5070181972 @default.
• W2077185818 hasConcept C102230213 @default.
• W2077185818 hasConcept C104317684 @default.
• W2077185818 hasConcept C126322002 @default.
• W2077185818 hasConcept C134018914 @default.
• W2077185818 hasConcept C141035611 @default.
• W2077185818 hasConcept C142724271 @default.
• W2077185818 hasConcept C170493617 @default.
• W2077185818 hasConcept C181152851 @default.
• W2077185818 hasConcept C203014093 @default.
• W2077185818 hasConcept C2775894120 @default.
• W2077185818 hasConcept C2776533406 @default.
• W2077185818 hasConcept C2777597313 @default.
• W2077185818 hasConcept C2778423431 @default.
• W2077185818 hasConcept C2779720271 @default.
• W2077185818 hasConcept C2780849966 @default.
• W2077185818 hasConcept C2780931953 @default.
• W2077185818 hasConcept C55493867 @default.
• W2077185818 hasConcept C71924100 @default.
• W2077185818 hasConcept C84393581 @default.
• W2077185818 hasConcept C86803240 @default.
• W2077185818 hasConcept C8891405 @default.
• W2077185818 hasConceptScore W2077185818C102230213 @default.
• W2077185818 hasConceptScore W2077185818C104317684 @default.
• W2077185818 hasConceptScore W2077185818C126322002 @default.
• W2077185818 hasConceptScore W2077185818C134018914 @default.

• next