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- W2077192533 abstract "In marine Vibrio species, the Vibrio harveyi-type LuxR protein, a key player in a quorum-sensing system, controls the expression of various genes. In this study, the luxR homologue in Vibrio alginolyticus was identified and named luxRval, whose expression was greatly induced by the increase of cell number. The luxRval in-frame deletion mutant showed a significant downregulation of total extracellular protease activity, and especially caused a 70% decrease in the transcript levels of extracellular alkaline serine protease A (proA), which was an important virulent factor of V. alginolyticus. Complementation in trans with luxRval could restore the expression of proA to the level of the wild-type strain. Deletion of the luxRval gene also resulted in changes of colony morphology, extracellular polysaccharide production and mobility. Therefore, another member of the V. harveyi-type LuxR regulator family has been characterized in V. alginolyticus." @default.
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- W2077192533 date "2008-08-01" @default.
- W2077192533 modified "2023-09-26" @default.
- W2077192533 title "Roles of LuxR in regulating extracellular alkaline serine protease A, extracellular polysaccharide and mobility of<i>Vibrio alginolyticus</i>" @default.
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- W2077192533 doi "https://doi.org/10.1111/j.1574-6968.2008.01185.x" @default.
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