FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2077192557> ?p ?o ?g. }

• W2077192557 endingPage "2150" @default.
• W2077192557 startingPage "2143" @default.
• W2077192557 abstract "Interaction of bovine serum albumin (BSA) with two series of dipolar molecules having both rigid and flexible structures has been studied by monitoring the spectral and temporal behavior of the intramolecular charge transfer fluorescence of the systems. The binding sites of the molecular systems in BSA have been located with the help of docking studies. Three different sites of varying hydrophobicity have been identified where these molecules are located. Binding in the hydrophobic domains of BSA leads to a blue shift of the fluorescence spectra and an enhancement of fluorescence intensity and lifetime. This enhancement is found to be the largest for flexible systems in which internal motion serves as a nonradiative decay route. In the BSA-bound condition, some of the dipolar molecules exhibit not-so-common dip-rise-dip time-resolved fluorescence anisotropy profiles. It is shown that a large difference of the fluorescence lifetimes of the protein-bound and unbound molecules is one of the factors that contributes to this kind of anisotropy profiles. As internal motion is often responsible for the short fluorescence lifetime of the flexible dipolar molecules, a large increase in the fluorescence lifetime of these systems occurs if binding to BSA leads to disruption/prevention of this motion. It thus appears that it might be possible to obtain information on the prevention/disruption of nonradiative pathway on protein binding from the anisotropy profiles of the kind discussed above. However, since the present study reveals cases where a large change in fluorescence lifetime also occurs due to other reasons, one needs to be careful prior to making any conclusion." @default.
• W2077192557 created "2016-06-24" @default.
• W2077192557 creator A5011161243 @default.
• W2077192557 creator A5051833773 @default.
• W2077192557 creator A5057340151 @default.
• W2077192557 creator A5084443827 @default.
• W2077192557 date "2009-01-28" @default.
• W2077192557 modified "2023-10-16" @default.
• W2077192557 title "Interaction of Bovine Serum Albumin with Dipolar Molecules: Fluorescence and Molecular Docking Studies" @default.
• W2077192557 cites W1950130060 @default.
• W2077192557 cites W1964900539 @default.
• W2077192557 cites W1965793914 @default.
• W2077192557 cites W1967630525 @default.
• W2077192557 cites W1968350058 @default.
• W2077192557 cites W1968720180 @default.
• W2077192557 cites W1973220529 @default.
• W2077192557 cites W1973238993 @default.
• W2077192557 cites W1974060561 @default.
• W2077192557 cites W1974116377 @default.
• W2077192557 cites W1978144767 @default.
• W2077192557 cites W1978301565 @default.
• W2077192557 cites W1985988481 @default.
• W2077192557 cites W1986191025 @default.
• W2077192557 cites W1989001433 @default.
• W2077192557 cites W1991113594 @default.
• W2077192557 cites W1993410968 @default.
• W2077192557 cites W1997295916 @default.
• W2077192557 cites W1999449827 @default.
• W2077192557 cites W1999796991 @default.
• W2077192557 cites W1999905943 @default.
• W2077192557 cites W2001314887 @default.
• W2077192557 cites W2004967666 @default.
• W2077192557 cites W2005785414 @default.
• W2077192557 cites W2007555801 @default.
• W2077192557 cites W2008166117 @default.
• W2077192557 cites W2008706286 @default.
• W2077192557 cites W2016401253 @default.
• W2077192557 cites W2016470740 @default.
• W2077192557 cites W2024315630 @default.
• W2077192557 cites W2029290832 @default.
• W2077192557 cites W2029403061 @default.
• W2077192557 cites W2031529709 @default.
• W2077192557 cites W2032496660 @default.
• W2077192557 cites W2037432273 @default.
• W2077192557 cites W2039883450 @default.
• W2077192557 cites W2041959385 @default.
• W2077192557 cites W2044535248 @default.
• W2077192557 cites W2049745418 @default.
• W2077192557 cites W2054085748 @default.
• W2077192557 cites W2060151241 @default.
• W2077192557 cites W2060615052 @default.
• W2077192557 cites W2060872258 @default.
• W2077192557 cites W2061977669 @default.
• W2077192557 cites W2065235336 @default.
• W2077192557 cites W2065283382 @default.
• W2077192557 cites W2065497508 @default.
• W2077192557 cites W2067508161 @default.
• W2077192557 cites W2067529228 @default.
• W2077192557 cites W2069506896 @default.
• W2077192557 cites W2069558639 @default.
• W2077192557 cites W2071486470 @default.
• W2077192557 cites W2075587839 @default.
• W2077192557 cites W2077964118 @default.
• W2077192557 cites W2082894729 @default.
• W2077192557 cites W2093684460 @default.
• W2077192557 cites W2095227081 @default.
• W2077192557 cites W2104236823 @default.
• W2077192557 cites W2129995310 @default.
• W2077192557 cites W2152604288 @default.
• W2077192557 cites W2158534713 @default.
• W2077192557 cites W2324501011 @default.
• W2077192557 cites W2337366399 @default.
• W2077192557 cites W2950276413 @default.
• W2077192557 cites W4211146992 @default.
• W2077192557 cites W4298287182 @default.
• W2077192557 doi "https://doi.org/10.1021/jp808611b" @default.
• W2077192557 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19199686" @default.
• W2077192557 hasPublicationYear "2009" @default.
• W2077192557 type Work @default.
• W2077192557 sameAs 2077192557 @default.
• W2077192557 citedByCount "129" @default.
• W2077192557 countsByYear W20771925572012 @default.
• W2077192557 countsByYear W20771925572013 @default.
• W2077192557 countsByYear W20771925572014 @default.
• W2077192557 countsByYear W20771925572015 @default.
• W2077192557 countsByYear W20771925572016 @default.
• W2077192557 countsByYear W20771925572017 @default.
• W2077192557 countsByYear W20771925572018 @default.
• W2077192557 countsByYear W20771925572019 @default.
• W2077192557 countsByYear W20771925572020 @default.
• W2077192557 countsByYear W20771925572021 @default.
• W2077192557 countsByYear W20771925572022 @default.
• W2077192557 countsByYear W20771925572023 @default.
• W2077192557 crossrefType "journal-article" @default.
• W2077192557 hasAuthorship W2077192557A5011161243 @default.
• W2077192557 hasAuthorship W2077192557A5051833773 @default.
• W2077192557 hasAuthorship W2077192557A5057340151 @default.
• W2077192557 hasAuthorship W2077192557A5084443827 @default.

• next