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• W2077263143 abstract "<b><i>Background: </i></b>Secondary hyperparathyroidism is associated with vascular calcification and arterial stiffness in patients with end-stage renal disease. The aim of this study was to analyze the frequency of intradialytic hypotension (IDH) and cardiovascular function before and after parathyroidectomy (PTX) in maintenance hemodialysis patients. <b><i>Methods: </i></b>We compared predialytic and intradialytic blood pressure, left and right ventricular ejection fraction (LVEF and RVEF), and cardiothoracic ratio 1 month before PTX, and 6 and 12 months after PTX. IDH was defined as a decrease in systolic blood pressure ≥ 20 mmHg or a decrease in mean arterial pressure ≥ 10 mmHg. <b><i>Results: </i></b>At the time of PTX, the mean age of the patients was 57.4 ± 12.0 years, and the mean dialysis vintage was 12.2 ± 5.8 years. At baseline, 6 months, and 12 months after PTX, the average numbers of sessions disturbed by IDH during 13 dialysis sessions (1 month) were 6.4, 3.9 (<i>p</i> < 0.016 <i>vs. </i>baseline), and 4.0 sessions (<i>p</i> < 0.037 <i>vs. </i>baseline, <i>p</i> = 0.801 <i>vs. </i>6 months), respectively. LVEF and RVEF were improved significantly after PTX. Furthermore, volume status was also improved, as evidenced by the significantly greater ultrafiltration volume and reduced cardiothoracic ratio. <b><i>Conclusions: </i></b>Hemodialysis patients with severe secondary hyperparathyroidism are more likely to achieve normotensive and euvolemic status after PTX, probably through improved heart function and reduced IDH episodes." @default.
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• W2077263143 date "2013-01-01" @default.
• W2077263143 modified "2023-10-17" @default.
• W2077263143 title "Parathyroidectomy Reduces Intradialytic Hypotension in Hemodialysis Patients with Secondary Hyperparathyroidism" @default.
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• W2077263143 doi "https://doi.org/10.1159/000350160" @default.
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