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• W2077285875 abstract "In this study, the protective effect of sweet potato extract against hydrogen peroxide-induced oxidative stress and cytotoxicity on the pheochromocytoma cell line (PC12) was investigated. The active component of the sweet potato extract was purified and determined to be 2,4-di-tert-butylphenol. The antioxidant capacity of 2,4-di-tert-butylphenol was measured by using 2,2′-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid (ABTS) radical. To examine the effects of 2,4-di-tert-butylphenol on amyloid-beta peptide (Aβ1-42)-induced learning and memory impairment in mice, in vivo behavioral tests were performed. Administration of 2,4-di-tert-butylphenol increased alternation behavior in mice injected with Aβ1-42. These results suggest that sweet potato extract could be protective against Aβ-induced neurotoxicity, possibly due to the antioxidative capacity of its constituent, 2,4-di-tert-butylphenol." @default.
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• W2077285875 date "2013-11-01" @default.
• W2077285875 modified "2023-10-10" @default.
• W2077285875 title "2,4-Di-<i>tert</i>-butylphenol from Sweet Potato Protects Against Oxidative Stress in PC12 Cells and in Mice" @default.
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• W2077285875 doi "https://doi.org/10.1089/jmf.2012.2739" @default.
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