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• W2077301822 abstract "The reinforcing effects of nicotine are mediated by brain regions that also support temporal difference error (TDE) processing; yet, the impact of nicotine on TDE is undetermined.Dependent smokers (n = 21) and matched control subjects (n = 21) were trained to associate a juice reward with a visual cue in a classical conditioning paradigm. Subjects subsequently underwent functional magnetic resonance imaging sessions in which they were exposed to trials where they either received juice as temporally predicted or where the juice was withheld (negative TDE) and later received unexpectedly (positive TDE). Subjects were scanned in two sessions that were identical, except that smokers had a transdermal nicotine (21 mg) or placebo patch placed before scanning. Analysis focused on regions along the trajectory of mesocorticolimbic and nigrostriatal dopaminergic pathways.There was a reduction in TDE-related function in smokers in the striatum, which did not differ as a function of patch manipulation but was predicted by the duration (years) of smoking. Activation in midbrain regions was not impacted by group or drug condition.These data suggest a differential effect of smoking status on the neural substrates of reward in distinct dopaminergic pathway regions, which may be partially attributable to chronic nicotine exposure. The failure of transdermal nicotine to alter reward-related functional processes, either within smokers or between smokers and control subjects, implies that acute nicotine patch administration is insufficient to modify reward processing, which has been linked to abstinence-induced anhedonia in smokers and may play a critical role in smoking relapse." @default.
• W2077301822 created "2016-06-24" @default.
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• W2077301822 date "2012-02-01" @default.
• W2077301822 modified "2023-10-12" @default.
• W2077301822 title "Chronic Exposure to Nicotine Is Associated with Reduced Reward-Related Activity in the Striatum but not the Midbrain" @default.
• W2077301822 cites W1032732133 @default.
• W2077301822 cites W1518079916 @default.
• W2077301822 cites W1522100687 @default.
• W2077301822 cites W1557320868 @default.
• W2077301822 cites W1579854617 @default.
• W2077301822 cites W1652173018 @default.
• W2077301822 cites W1782902465 @default.
• W2077301822 cites W1965914801 @default.
• W2077301822 cites W1978214003 @default.
• W2077301822 cites W1978702556 @default.
• W2077301822 cites W1985408870 @default.
• W2077301822 cites W1987219819 @default.
• W2077301822 cites W1994175579 @default.
• W2077301822 cites W1994728257 @default.
• W2077301822 cites W1998152406 @default.
• W2077301822 cites W2002352860 @default.
• W2077301822 cites W2003505635 @default.
• W2077301822 cites W2004618736 @default.
• W2077301822 cites W2018086419 @default.
• W2077301822 cites W2019293912 @default.
• W2077301822 cites W2020005121 @default.
• W2077301822 cites W2029948352 @default.
• W2077301822 cites W2033053358 @default.
• W2077301822 cites W2035387730 @default.
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• W2077301822 cites W2045274199 @default.
• W2077301822 cites W2046517881 @default.
• W2077301822 cites W2049324875 @default.
• W2077301822 cites W2051648601 @default.
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• W2077301822 cites W2067874550 @default.
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• W2077301822 cites W2075940117 @default.
• W2077301822 cites W2080839667 @default.
• W2077301822 cites W2082275787 @default.
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• W2077301822 cites W2090957966 @default.
• W2077301822 cites W2091673195 @default.
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• W2077301822 cites W2114104729 @default.
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• W2077301822 cites W2117140276 @default.
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• W2077301822 cites W2126449078 @default.
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• W2077301822 doi "https://doi.org/10.1016/j.biopsych.2011.09.013" @default.
• W2077301822 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3253900" @default.
• W2077301822 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22032832" @default.
• W2077301822 hasPublicationYear "2012" @default.
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