Matches in SemOpenAlex for { <https://semopenalex.org/work/W2077305004> ?p ?o ?g. }
- W2077305004 endingPage "717" @default.
- W2077305004 startingPage "710" @default.
- W2077305004 abstract "Acute myocardial infarction (AMI), is related to a diffuse active inflammation of the coronary tree associated with rupture of one of the multiple vulnerable plaques. The presence of soluble mediators of inflammation with their synergic or antagonistic actions coordinates the physiological response determining the plaque fate and the fatal event. The present study focus on the cytokines network operating in human coronary plaques of patients died from AMI and controls, pointing out that coronaries of AMI patients produce PTX3 protein twice as that of controls and express high level of PTX3 mRNA.The presence of CX3CR1 polymorphisms is significantly correlated with the incidence and the outcome of acute myocardial infarction inducing in the whole coronary tree a strong recruitment of Th1 polarized inflammation that is directly correlated to PTX3 expression.Moreover we found a positive correlation between the expression of PTX3 in the plaque and the content of macrophage cells showing a M2 polarization indicating the possible role of this chemokine as mediator of immune response that would orchestrate plaque evolution and inflammatory cell type activation." @default.
- W2077305004 created "2016-06-24" @default.
- W2077305004 creator A5012763047 @default.
- W2077305004 creator A5014812082 @default.
- W2077305004 creator A5016903134 @default.
- W2077305004 creator A5023560919 @default.
- W2077305004 creator A5053787935 @default.
- W2077305004 creator A5085756513 @default.
- W2077305004 date "2014-10-01" @default.
- W2077305004 modified "2023-10-18" @default.
- W2077305004 title "PTX3: A modulator of human coronary plaque vulnerability acting by macrophages type 2" @default.
- W2077305004 cites W1501778305 @default.
- W2077305004 cites W1963651122 @default.
- W2077305004 cites W1964369726 @default.
- W2077305004 cites W1968998370 @default.
- W2077305004 cites W1969095061 @default.
- W2077305004 cites W1972790678 @default.
- W2077305004 cites W1993215640 @default.
- W2077305004 cites W1994840834 @default.
- W2077305004 cites W1994980657 @default.
- W2077305004 cites W2003768727 @default.
- W2077305004 cites W201422399 @default.
- W2077305004 cites W2032508585 @default.
- W2077305004 cites W2049793799 @default.
- W2077305004 cites W2054665792 @default.
- W2077305004 cites W2079299921 @default.
- W2077305004 cites W2086611357 @default.
- W2077305004 cites W2093956332 @default.
- W2077305004 cites W2094941678 @default.
- W2077305004 cites W2102785524 @default.
- W2077305004 cites W2108480363 @default.
- W2077305004 cites W2109450293 @default.
- W2077305004 cites W2113186517 @default.
- W2077305004 cites W2130932880 @default.
- W2077305004 cites W2138420245 @default.
- W2077305004 cites W2142563319 @default.
- W2077305004 cites W2142738135 @default.
- W2077305004 cites W2155493360 @default.
- W2077305004 cites W2156593520 @default.
- W2077305004 cites W2156867452 @default.
- W2077305004 cites W2157321333 @default.
- W2077305004 cites W2157868854 @default.
- W2077305004 cites W2158987986 @default.
- W2077305004 cites W2161110273 @default.
- W2077305004 cites W2161637204 @default.
- W2077305004 cites W2161682643 @default.
- W2077305004 cites W2163114658 @default.
- W2077305004 cites W2169989044 @default.
- W2077305004 cites W2335455113 @default.
- W2077305004 doi "https://doi.org/10.1016/j.ijcard.2014.07.109" @default.
- W2077305004 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25131923" @default.
- W2077305004 hasPublicationYear "2014" @default.
- W2077305004 type Work @default.
- W2077305004 sameAs 2077305004 @default.
- W2077305004 citedByCount "13" @default.
- W2077305004 countsByYear W20773050042014 @default.
- W2077305004 countsByYear W20773050042015 @default.
- W2077305004 countsByYear W20773050042016 @default.
- W2077305004 countsByYear W20773050042017 @default.
- W2077305004 countsByYear W20773050042018 @default.
- W2077305004 countsByYear W20773050042019 @default.
- W2077305004 countsByYear W20773050042020 @default.
- W2077305004 countsByYear W20773050042022 @default.
- W2077305004 countsByYear W20773050042023 @default.
- W2077305004 crossrefType "journal-article" @default.
- W2077305004 hasAuthorship W2077305004A5012763047 @default.
- W2077305004 hasAuthorship W2077305004A5014812082 @default.
- W2077305004 hasAuthorship W2077305004A5016903134 @default.
- W2077305004 hasAuthorship W2077305004A5023560919 @default.
- W2077305004 hasAuthorship W2077305004A5053787935 @default.
- W2077305004 hasAuthorship W2077305004A5085756513 @default.
- W2077305004 hasConcept C126322002 @default.
- W2077305004 hasConcept C127901578 @default.
- W2077305004 hasConcept C13373296 @default.
- W2077305004 hasConcept C164705383 @default.
- W2077305004 hasConcept C185592680 @default.
- W2077305004 hasConcept C202751555 @default.
- W2077305004 hasConcept C203014093 @default.
- W2077305004 hasConcept C2776914184 @default.
- W2077305004 hasConcept C2779244956 @default.
- W2077305004 hasConcept C500558357 @default.
- W2077305004 hasConcept C55493867 @default.
- W2077305004 hasConcept C71924100 @default.
- W2077305004 hasConcept C8891405 @default.
- W2077305004 hasConceptScore W2077305004C126322002 @default.
- W2077305004 hasConceptScore W2077305004C127901578 @default.
- W2077305004 hasConceptScore W2077305004C13373296 @default.
- W2077305004 hasConceptScore W2077305004C164705383 @default.
- W2077305004 hasConceptScore W2077305004C185592680 @default.
- W2077305004 hasConceptScore W2077305004C202751555 @default.
- W2077305004 hasConceptScore W2077305004C203014093 @default.
- W2077305004 hasConceptScore W2077305004C2776914184 @default.
- W2077305004 hasConceptScore W2077305004C2779244956 @default.
- W2077305004 hasConceptScore W2077305004C500558357 @default.
- W2077305004 hasConceptScore W2077305004C55493867 @default.
- W2077305004 hasConceptScore W2077305004C71924100 @default.
- W2077305004 hasConceptScore W2077305004C8891405 @default.
- W2077305004 hasIssue "3" @default.