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• W2077305470 abstract "Planar lipid bilayer membranes are formed from mixtures of pure lipids in the absence of non-biological solvents. The solventless bilayers are characterized by a large specific capacitance (586–957 nF/cm2) comparable to that of cell membranes but considerably greater than that of conventional lipid/decane bilayers. Hydrocarbon solvents, such as n-alkanes or squalene, thicken the bilayer. Membrane dielectric thickness is used as an indicator of bilayer lipid composition. For membranes made from pure monoglyceride/triglyceride mixtures the thickness of the solventless lipid bilayer is independent of both the chain length (11–22 carbons) and mol fraction (0.1–0.9) of triglyceride in the bulk mixture. In contrast, the thickness of the bilayer (2.0–3.3 nm) depends strongly upon the length (16–24 carbons) of the monoglyceride component. Molecular volume considerations lead to the conclusion that the bulk lipid mixture disproportionates to yield bilayer membranes composed of nearly pure monoglyceride. The dielectric thickness of the monoglyceride bilayer is consistent with the notion that the lipid fatty acyl chains are fluid." @default.
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• W2077305470 date "1979-11-01" @default.
• W2077305470 modified "2023-09-25" @default.
• W2077305470 title "Planar bilayer membranes from pure lipids" @default.
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• W2077305470 doi "https://doi.org/10.1016/0005-2736(79)90328-6" @default.
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