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- W2077309466 abstract "A variety of different categories of contrast agents, and within each category a number of individual agents, are currently available for clinical use in magnetic resonance (MR) imaging of the liver. In this review, the use of nonspecific extracellular gadolinium chelates, reticuloendothelial system-specific iron oxide particulate agents, hepatocyte-selective agents, and combined perfusion and hepatocyte-selective agents are described. Most clinical experience is with nonspecific extracellular gadolinium chelates. The relatively low cost, safety, good patient tolerance, and ability to help detect and characterize a wide range of liver diseases have rendered gadolinium chelates as commonly used agents. Reticuloendothelial system-specific agents improve lesion detection by decreasing the signal intensity of background liver on T2-weighted MR images, which increases the conspicuity of focal hepatic lesions with negligible reticuloendothelial cells (eg, metastases). Hepatocyte-selective agents increase the signal intensity of background liver on T1-weighted images, which increases the conspicuity of focal lesions that do not contain hepatocytes (eg, metastases). The clinical application of the different categories of contrast agents, techniques for their administration, sequences to be used, and appearances of common entities on contrast agent-enhanced studies are described." @default.
- W2077309466 created "2016-06-24" @default.
- W2077309466 creator A5021395037 @default.
- W2077309466 creator A5061857655 @default.
- W2077309466 date "2001-01-01" @default.
- W2077309466 modified "2023-10-18" @default.
- W2077309466 title "Contrast Agents for MR Imaging of the Liver" @default.
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- W2077309466 doi "https://doi.org/10.1148/radiology.218.1.r01ja2427" @default.
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