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- W2077320577 abstract "A 3.2 kbp human genomic DNA fragment (BamHI-Sau3A) of the 3{prime} untranslated and 3{prime} flanking region of the CKMM gene was isolated and subcloned into the BamHI site of vector pSP64. The CKMM 3{prime}-probe identifies a 2-allele polymorphism with bands at 2.3 and 1.0 kbp (allele A) and 3.3 kbp (allele B). In addition a weak constant 4.2 kbp band is observed. This probe also detects a 2-allele TaqI RFLP reported previously, as either a 4.3 kbp (A) or a 4.2 kbp (B) band. The CKMM locus previously has been assigned to 19q13.2-q13.3. By Southern blot analysis of human-rodent somatic cell hybrids containing unique subregional fragments of chromosome 19 of man the authors have assigned the gene to 19q13.2. Co-dominant segregation was observed in 8 families with 3 generations." @default.
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- W2077320577 date "1988-01-01" @default.
- W2077320577 modified "2023-10-18" @default.
- W2077320577 title "NcoI RFLP at the creatine kinase-muscle type gene locus (CKMM, chromosome 19)" @default.
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- W2077320577 doi "https://doi.org/10.1093/nar/16.17.8743" @default.
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