FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2077335983> ?p ?o ?g. }

• W2077335983 endingPage "668" @default.
• W2077335983 startingPage "657" @default.
• W2077335983 abstract "Clinical-chemical traits are essential when examining the health status of individuals. The aim of this study was to identify quantitative trait loci (QTL) and the associated positional candidate genes affecting clinical-chemical traits in a reciprocal F 2 intercross between Landrace and Korean native pigs. Following an overnight fast, 25 serum phenotypes related to clinical-chemical traits (e.g., hepatic function parameters, renal function parameters, electrolyte, lipids) were measured in >970 F 2 progeny. All experimental samples were subjected to genotyping analysis using 165 microsatellite markers located across the genome. We identified eleven genome-wide significant QTL in six chromosomal regions (SSC 2, 7, 8, 13, 14, and 15) and 59 suggestive QTL in 17 chromosomal regions (SSC 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 12, 13, 14, 15, 16, 17, and 18). We also observed significant effects of reciprocal crosses on some of the traits, which would seem to result from maternal effect, QTL on sex chromosomes, imprinted genes, or genetic difference in mitochondrial DNA. The role of genomic imprinting in clinical-chemical traits also was investigated. Genome-wide analysis revealed a significant evidence for an imprinted QTL in SSC4 affecting serum amylase levels. Additionally, a series of bivariate linkage analysis provided strong evidence that QTL in SSC 2, 13, 15, and 18 have a pleiotropic effect on clinical-chemical traits. In conclusion, our study detected both novel and previously reported QTL influencing clinical-chemical traits in pigs. The identified QTL together with the positional candidate genes identified here could play an important role in elucidating the genetic structure of clinical-chemical phenotype variation in humans and swine." @default.
• W2077335983 created "2016-06-24" @default.
• W2077335983 creator A5004454370 @default.
• W2077335983 creator A5005183914 @default.
• W2077335983 creator A5005202906 @default.
• W2077335983 creator A5026411254 @default.
• W2077335983 creator A5055726943 @default.
• W2077335983 creator A5058126879 @default.
• W2077335983 creator A5058377433 @default.
• W2077335983 creator A5064973569 @default.
• W2077335983 creator A5069875641 @default.
• W2077335983 creator A5072152965 @default.
• W2077335983 creator A5083151420 @default.
• W2077335983 creator A5085190091 @default.
• W2077335983 date "2012-07-01" @default.
• W2077335983 modified "2023-10-07" @default.
• W2077335983 title "QTL analysis of clinical-chemical traits in an F₂intercross between Landrace and Korean native pigs" @default.
• W2077335983 cites W1540326034 @default.
• W2077335983 cites W1548014564 @default.
• W2077335983 cites W1572023751 @default.
• W2077335983 cites W1901338077 @default.
• W2077335983 cites W1939671230 @default.
• W2077335983 cites W1971247041 @default.
• W2077335983 cites W1975237980 @default.
• W2077335983 cites W1977066990 @default.
• W2077335983 cites W1978018049 @default.
• W2077335983 cites W1978546032 @default.
• W2077335983 cites W1982959726 @default.
• W2077335983 cites W1988078996 @default.
• W2077335983 cites W2002941616 @default.
• W2077335983 cites W2007469377 @default.
• W2077335983 cites W2020320027 @default.
• W2077335983 cites W2025465543 @default.
• W2077335983 cites W2041237913 @default.
• W2077335983 cites W2047524069 @default.
• W2077335983 cites W2049672602 @default.
• W2077335983 cites W2050759324 @default.
• W2077335983 cites W2053624352 @default.
• W2077335983 cites W2054418908 @default.
• W2077335983 cites W2060293383 @default.
• W2077335983 cites W2062549773 @default.
• W2077335983 cites W2070843278 @default.
• W2077335983 cites W2076184177 @default.
• W2077335983 cites W2082397102 @default.
• W2077335983 cites W2089163597 @default.
• W2077335983 cites W2094935361 @default.
• W2077335983 cites W2097324008 @default.
• W2077335983 cites W2099057503 @default.
• W2077335983 cites W2109085886 @default.
• W2077335983 cites W2125217713 @default.
• W2077335983 cites W2125860227 @default.
• W2077335983 cites W2126564109 @default.
• W2077335983 cites W2126810330 @default.
• W2077335983 cites W2128326754 @default.
• W2077335983 cites W2129674490 @default.
• W2077335983 cites W2136124687 @default.
• W2077335983 cites W2143286837 @default.
• W2077335983 cites W2146341872 @default.
• W2077335983 cites W2147295426 @default.
• W2077335983 cites W2148576593 @default.
• W2077335983 cites W2150062053 @default.
• W2077335983 cites W2150943752 @default.
• W2077335983 cites W2152992515 @default.
• W2077335983 cites W2160427718 @default.
• W2077335983 cites W2161527180 @default.
• W2077335983 cites W2163789582 @default.
• W2077335983 cites W2169294950 @default.
• W2077335983 cites W2319036533 @default.
• W2077335983 cites W4211095212 @default.
• W2077335983 cites W4229886032 @default.
• W2077335983 doi "https://doi.org/10.1152/physiolgenomics.00172.2011" @default.
• W2077335983 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22496488" @default.
• W2077335983 hasPublicationYear "2012" @default.
• W2077335983 type Work @default.
• W2077335983 sameAs 2077335983 @default.
• W2077335983 citedByCount "11" @default.
• W2077335983 countsByYear W20773359832012 @default.
• W2077335983 countsByYear W20773359832013 @default.
• W2077335983 countsByYear W20773359832014 @default.
• W2077335983 countsByYear W20773359832016 @default.
• W2077335983 countsByYear W20773359832018 @default.
• W2077335983 countsByYear W20773359832019 @default.
• W2077335983 countsByYear W20773359832020 @default.
• W2077335983 countsByYear W20773359832021 @default.
• W2077335983 countsByYear W20773359832023 @default.
• W2077335983 crossrefType "journal-article" @default.
• W2077335983 hasAuthorship W2077335983A5004454370 @default.
• W2077335983 hasAuthorship W2077335983A5005183914 @default.
• W2077335983 hasAuthorship W2077335983A5005202906 @default.
• W2077335983 hasAuthorship W2077335983A5026411254 @default.
• W2077335983 hasAuthorship W2077335983A5055726943 @default.
• W2077335983 hasAuthorship W2077335983A5058126879 @default.
• W2077335983 hasAuthorship W2077335983A5058377433 @default.
• W2077335983 hasAuthorship W2077335983A5064973569 @default.
• W2077335983 hasAuthorship W2077335983A5069875641 @default.
• W2077335983 hasAuthorship W2077335983A5072152965 @default.
• W2077335983 hasAuthorship W2077335983A5083151420 @default.
• W2077335983 hasAuthorship W2077335983A5085190091 @default.

• next