Matches in SemOpenAlex for { <https://semopenalex.org/work/W2077338178> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2077338178 endingPage "1332" @default.
- W2077338178 startingPage "1326" @default.
- W2077338178 abstract "Sarcoidosis is a multisystem granulomatous disorder of unknown etiology. Hereditary etiology has been proposed as a cause of the sarcoidosis, and some Human Leucocyte Antigen (HLA) alleles have been related to the diagnosis or severity of the disease. Löfgren’s syndrome has been linked to patients with the DRB1*03 allele, and non-resolving disease has been associated with the DRB1*07, DRB1*14 and DRB1*15 alleles. However, the results observed in Caucasian patients are not reproducible in other populations, such as in Japanese individuals. The aim of this study is to examine the HLA alleles in Brazilian patients with sarcoidosis confirmed by biopsy. Sixty-three patients were included in the study, and the HLA alleles were compared with 126 control individuals. HLA-A, -B, -C, -DRB1 and -DQB1 genes were typed using a Luminex Multi-analyte profiling system (One Lambda, Inc. Canoga Park, CA). Among sarcoidosis patients, the HLA A*23, A*80, B*08, B*41, DQB1*05 and DRB1*14 antigens tended to be more common than in the controls, whereas the B*44, B*45, B*51, B*58, DRB1*15 and DRB1*16 alleles were more frequently found in control subjects than in the sarcoidosis patients. However, after Bonferroni correction, only the HLA-DRB1*14 allele was found to be significantly different between sarcoidosis patients and controls (pC = 0.0047, OR = 11.69, CI = 2.47–55.22). This allele was more frequent in mestizos and black patients. The presence of an HLA-DRB1*14 allele might determine the risk of sarcoidosis in Brazilian individuals, especially in mestizos and black patients." @default.
- W2077338178 created "2016-06-24" @default.
- W2077338178 creator A5002940982 @default.
- W2077338178 creator A5028031403 @default.
- W2077338178 creator A5045038169 @default.
- W2077338178 creator A5060880224 @default.
- W2077338178 creator A5063410172 @default.
- W2077338178 creator A5085594814 @default.
- W2077338178 date "2013-10-01" @default.
- W2077338178 modified "2023-09-27" @default.
- W2077338178 title "HLA in a cohort of Brazilian patients with sarcoidosis" @default.
- W2077338178 cites W103689365 @default.
- W2077338178 cites W1962078396 @default.
- W2077338178 cites W1973309339 @default.
- W2077338178 cites W1976464271 @default.
- W2077338178 cites W1984424987 @default.
- W2077338178 cites W1993111686 @default.
- W2077338178 cites W2001599098 @default.
- W2077338178 cites W2003017252 @default.
- W2077338178 cites W2037682100 @default.
- W2077338178 cites W2056863340 @default.
- W2077338178 cites W2056929932 @default.
- W2077338178 cites W2058345740 @default.
- W2077338178 cites W2060822035 @default.
- W2077338178 cites W2114661044 @default.
- W2077338178 cites W2123742572 @default.
- W2077338178 cites W2142577289 @default.
- W2077338178 cites W2147656643 @default.
- W2077338178 cites W2166119736 @default.
- W2077338178 cites W4239149238 @default.
- W2077338178 doi "https://doi.org/10.1016/j.humimm.2013.07.009" @default.
- W2077338178 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23911360" @default.
- W2077338178 hasPublicationYear "2013" @default.
- W2077338178 type Work @default.
- W2077338178 sameAs 2077338178 @default.
- W2077338178 citedByCount "4" @default.
- W2077338178 countsByYear W20773381782014 @default.
- W2077338178 countsByYear W20773381782018 @default.
- W2077338178 countsByYear W20773381782020 @default.
- W2077338178 countsByYear W20773381782023 @default.
- W2077338178 crossrefType "journal-article" @default.
- W2077338178 hasAuthorship W2077338178A5002940982 @default.
- W2077338178 hasAuthorship W2077338178A5028031403 @default.
- W2077338178 hasAuthorship W2077338178A5045038169 @default.
- W2077338178 hasAuthorship W2077338178A5060880224 @default.
- W2077338178 hasAuthorship W2077338178A5063410172 @default.
- W2077338178 hasAuthorship W2077338178A5085594814 @default.
- W2077338178 hasConcept C104317684 @default.
- W2077338178 hasConcept C126322002 @default.
- W2077338178 hasConcept C137627325 @default.
- W2077338178 hasConcept C147483822 @default.
- W2077338178 hasConcept C180754005 @default.
- W2077338178 hasConcept C188280979 @default.
- W2077338178 hasConcept C203014093 @default.
- W2077338178 hasConcept C2779134260 @default.
- W2077338178 hasConcept C2781301800 @default.
- W2077338178 hasConcept C37463918 @default.
- W2077338178 hasConcept C54355233 @default.
- W2077338178 hasConcept C71924100 @default.
- W2077338178 hasConcept C86803240 @default.
- W2077338178 hasConceptScore W2077338178C104317684 @default.
- W2077338178 hasConceptScore W2077338178C126322002 @default.
- W2077338178 hasConceptScore W2077338178C137627325 @default.
- W2077338178 hasConceptScore W2077338178C147483822 @default.
- W2077338178 hasConceptScore W2077338178C180754005 @default.
- W2077338178 hasConceptScore W2077338178C188280979 @default.
- W2077338178 hasConceptScore W2077338178C203014093 @default.
- W2077338178 hasConceptScore W2077338178C2779134260 @default.
- W2077338178 hasConceptScore W2077338178C2781301800 @default.
- W2077338178 hasConceptScore W2077338178C37463918 @default.
- W2077338178 hasConceptScore W2077338178C54355233 @default.
- W2077338178 hasConceptScore W2077338178C71924100 @default.
- W2077338178 hasConceptScore W2077338178C86803240 @default.
- W2077338178 hasIssue "10" @default.
- W2077338178 hasLocation W20773381781 @default.
- W2077338178 hasLocation W20773381782 @default.
- W2077338178 hasOpenAccess W2077338178 @default.
- W2077338178 hasPrimaryLocation W20773381781 @default.
- W2077338178 hasRelatedWork W2069207898 @default.
- W2077338178 hasRelatedWork W2077338178 @default.
- W2077338178 hasRelatedWork W2085748103 @default.
- W2077338178 hasRelatedWork W2099041497 @default.
- W2077338178 hasRelatedWork W2120316643 @default.
- W2077338178 hasRelatedWork W2369761141 @default.
- W2077338178 hasRelatedWork W2404446324 @default.
- W2077338178 hasRelatedWork W2435931953 @default.
- W2077338178 hasRelatedWork W2540336298 @default.
- W2077338178 hasRelatedWork W937842968 @default.
- W2077338178 hasVolume "74" @default.
- W2077338178 isParatext "false" @default.
- W2077338178 isRetracted "false" @default.
- W2077338178 magId "2077338178" @default.
- W2077338178 workType "article" @default.