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- W2077340368 abstract "The phytochemical composition of passionfruit juice (PFJ) was hypothesized to have valuable anti-cancer activity, and this was tested in a BALB/c 3T3 neoplastic transformation model. A higher concentration of PFJ compared with a lower concentration was effective in reducing the number, size, and invasiveness of transformed foci. When incubated with another mammalian cell line, the MOLT-4, PFJ was unable to alter the cell cycle kinetics while at the same time was successful in inducing the activity of caspase-3, an enzyme that commits the cell to apoptosis. This suggests that phytochemicals found in PFJ were able to produce the changes in transformed foci due to apoptotic mechanisms rather than by a reduction in cell proliferation. These beneficial results were achieved at levels that could theoretically be attained in the plasma after consumption of the juice." @default.
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- W2077340368 date "2004-12-01" @default.
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- W2077340368 title "Inhibition of Neoplastic Transformation of Benzo[α]pyrene-Treated BALB/c 3T3 Murine Cells by a Phytochemical Extract of Passionfruit Juice" @default.
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- W2077340368 doi "https://doi.org/10.1089/jmf.2004.7.402" @default.
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