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- W2077358658 abstract "Few studies have addressed the prenatal detection rate of congenital heart defects in a non-selected population at 18 weeks of gestation. Our objective was to assess the change in the prenatal detection rate of congenital heart defects in such a population that resulted from incorporating the four-chamber view at the second- trimester routine ultrasound examination. The prenatal detection rate of heart defects was prospectively compared between 4435 fetuses in Phase I who were stunned without special attention to the heart, and 7459 fetuses in Phase II who were scanned incorporating the four-chamber view. Of the 49 heart defects in Phase I, 17 (35%) were critical and three (18%) of these were detected prenatally. Of the 90 heart defects in Phase II, 23 (26%) were critical, six (26%) of these were detected prenatally at the 18 weeks' routine stun, and three were detected in the third trimester, providing a total prenatal detection rate of 39%. A defect was classified as critical when a surgical repair was likely to be required because of gross structural complexity having a functional significance, e.g. transposition of the great arteries, hypo-plastic left heart syndrome, atrioventricular septal defect, coarctation of the aorta, and large ventricular septal defect. No non-critical heart defects were detected prenatally in either of the phases. The incidences in the total population were 11 and 12/1000 in Phases I and II, respectively. Thirty-two per cent of the critical and 16% of the non-critical defects had associated abnormalities and/or abnormal karyotype. Implementation of the four-chamber view increased the prenatal detection rate of critical heart defects. To improve the results significantly, education and an extended fetal heart examination are necessary. Copyright © 1995 International Society of Ultrasound in Obstetrics and Gynecology" @default.
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- W2077358658 date "1995-06-01" @default.
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- W2077358658 title "Prenatal detection of heart defects at the routine fetal examination at 18 weeks in a non-selected population" @default.
- W2077358658 doi "https://doi.org/10.1046/j.1469-0705.1995.05060372.x" @default.
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