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• W2077410145 endingPage "48" @default.
• W2077410145 startingPage "42" @default.
• W2077410145 abstract "The neurotransmitter dopamine (DA) plays a critical role in CNS circuits that provide for attention, executive function, reward responses, motivation and movement. DA is inactivated by the cocaine- and amphetamine-sensitive DA transporter (DAT), a protein that also provides a pathway for non-vesicular DA release. After a brief review of DAT function and psychostimulant actions, we consider the importance DAT in relation to the distinct firing patterns of DA neurons that permit awareness of novelty and reward. Finally, we review recent efforts to gather direct support for DAT-linked disorders, with a specific focus on DAT mutations recently identified in subjects with ADHD." @default.
• W2077410145 created "2016-06-24" @default.
• W2077410145 creator A5022425643 @default.
• W2077410145 creator A5025174055 @default.
• W2077410145 creator A5053184160 @default.
• W2077410145 date "2014-07-01" @default.
• W2077410145 modified "2023-09-23" @default.
• W2077410145 title "Good riddance to dopamine: Roles for the dopamine transporter in synaptic function and dopamine-associated brain disorders" @default.
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