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- W2077440068 abstract "A preliminary communication is presented on the intravenous injection of hyaluronidase in acute myocardial infarction. Six cases are reported and electrocardiographic changes are shown after the administration of the drug. The results of studies in seven dogs are reported. Apparently, hyaluronidase acts by reducing intramyocardial edema during the acute phase following coronary occlusion. The physiopathology of this intramyocardial edema is discussed, as well as the possible mechanisms of action of this enzyme. The authors stress the necessity of further investigations before hyaluronidase can be accepted as an efficient drug in the management of acute myocardial infarction." @default.
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- W2077440068 date "1959-05-01" @default.
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- W2077440068 title "Intravenous injection of hyaluronidase in acute myocardial infarction: Preliminary report of clinical and experimental observations" @default.
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- W2077440068 doi "https://doi.org/10.1016/0002-8703(59)90180-2" @default.
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