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• W2077471279 abstract "It is important in most radiation experiments to have both a quantitative measure of the amount of radiation involved, and a qualitative description of the radiation which uniquely defines its significant properties. The required quantitative measure is the absorbed dose, which is the amount of energy absorbed per unit mass of the irradiated material. This can be expressed in rads (1 rad = 100 ergs/gm.). The most pertinent qualitative description is that of the spatial distribution of the collisions by which the electrons (or other ionizing and exciting particles) which are responsible for the actual energy dissipation lose their energy. This concept has been termed “linear energy transfer” (LET) and is defined in terms of the energy lost per unit path length by the particle (1, p. 6). The LET is usually written as a function, L(T), of the kinetic energy, T, of the particle and is conveniently expressed in units of kev/µ where µ is 1 micron of path length. The significant information concerning the distribution of LET in the interior of the irradiated medium is given by the total amount of track length involved per unit LET interval. The distribution of track length as a function of LET will then be n(L), which is really the ionizing particle flux written as a function of L(T) instead of the particle kinetic energy T. Calculation of the primary electron source spectrum and the resultant primary slowing-down flux and LET distributions in water have already been reported by Cormack and Johns (2) for a wide range of x-ray energies used at present in therapeutic installations. In the calculations of these investigators the space-independent assumption was made that the spectrum of the x-ray beam remained constant in the interior of the irradiated medium. This restriction was removed in the high-energy region by the work of Brysk and Goldman (3), which enables calculations to be made as a function of depth of penetration. Calculations which include the total electron spectrum have been made by Burch (4), again with the assumption of space independence. We have made similar calculations of the total electron spectrum, using some results of Spencer and Attix (5), and the conclusions are compared with those of Burch. The calculations to be presented in this paper are concerned with the methods of obtaining the absorbed dose D from cavity ionization measurements, and with the evaluation of the LET distribution function n(L). The calculations have been made for seven photon spectra: (1) 130 kvcp, 5 mm. Al h.v.l.; (2) 200 kvcp, 0.5 mm. Cu h.v.l.: (3) 250 kvcp, 1 mm. Cu h.v.l.; (4) 250 kvcp, 2 mm. Cu h.v.l.: (5) 1 Mevp, 3.4 mm. Pb h.v.l.; (6) Co60 gamma rays; (7) 25 Mevp (betatron) x-rays, uncompensated. Photon spectra 1–5 were derived with use of a simplified linear Kramer's plot for the continuous thick target emission spectrum with the attenuation of the interposed filtering material taken into consideration." @default.
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• W2077471279 title "Absorbed Dose and Linear Energy Transfer in Radiation Experiments" @default.
• W2077471279 doi "https://doi.org/10.1148/72.1.51" @default.
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