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• W2077488822 abstract "The fluorescence plus Giemsa (FPG) and fluorescence in situ hybridization (FISH) techniques have been used to determine, respectively, the frequencies of sister chromatid exchanges (SCEs) and stable chromosome aberrations (translocations) induced by different concentrations of BrdU in the Chinese hamster ovary cell mutant EM9 and its parental line AA8. The results indicate that BrdU induced a high frequency of SCEs and translocations in EM9 as compared with AA8, and that the translocation/dicentric ratio was also higher in the mutant cell line than in the parental cell line in both untreated and BrdU-treated cultures. These observations may indicate a possible relationship between the molecular mechanisms involved in the formation of SCEs and translocations." @default.
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• W2077488822 date "1998-02-01" @default.
• W2077488822 modified "2023-10-07" @default.
• W2077488822 title "A high yield of translocations parallels the high yield of sister chromatid exchanges in the CHO mutant EM9" @default.
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• W2077488822 doi "https://doi.org/10.1016/s0027-5107(97)00241-8" @default.
• W2077488822 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9626966" @default.
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