FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2077507754> ?p ?o ?g. }

• W2077507754 endingPage "1774" @default.
• W2077507754 startingPage "1766" @default.
• W2077507754 abstract "There is controversy in the literature concerning the action of tetrahydropterines on the enzyme tyrosinase and on melanogenesis in general. In this study, we demonstrate that tetrahydropterines can inhibit melanogenesis in several ways: i) by non-enzymatic inhibition involving purely chemical reactions reducing o-dopaquinone to L-dopa, ii) by acting as substrates which compete with L-tyr and L-dopa, since they are substrates of tyrosinase; and iii) by irreversibly inhibiting the enzymatic forms met-tyrosinase and deoxy-tyrosinase in anaerobic conditions. Three tetrahydropterines have been kinetically characterised as tyrosinase substrates: 6-R-L-erythro-5,6,7,8-tetrahydrobiopterin, 6-methyl-5,6,7,8-tetrahydropterine and 6,7-(R,S)-dimethyl-5,6,7,8-tetrahydropterine. A kinetic reaction mechanism is proposed to explain the oxidation of these compounds by tyrosinase." @default.
• W2077507754 created "2016-06-24" @default.
• W2077507754 creator A5016590260 @default.
• W2077507754 creator A5035002495 @default.
• W2077507754 creator A5039253271 @default.
• W2077507754 creator A5055149878 @default.
• W2077507754 creator A5059176966 @default.
• W2077507754 creator A5077658470 @default.
• W2077507754 creator A5086418754 @default.
• W2077507754 date "2009-12-01" @default.
• W2077507754 modified "2023-10-18" @default.
• W2077507754 title "Melanogenesis inhibition by tetrahydropterines" @default.
• W2077507754 cites W1497427077 @default.
• W2077507754 cites W1557847147 @default.
• W2077507754 cites W1571821264 @default.
• W2077507754 cites W1969367314 @default.
• W2077507754 cites W1973903359 @default.
• W2077507754 cites W1976454537 @default.
• W2077507754 cites W1977643269 @default.
• W2077507754 cites W1990461363 @default.
• W2077507754 cites W1992522075 @default.
• W2077507754 cites W2001061859 @default.
• W2077507754 cites W2019630110 @default.
• W2077507754 cites W2019894619 @default.
• W2077507754 cites W2028291957 @default.
• W2077507754 cites W2032852028 @default.
• W2077507754 cites W2041404481 @default.
• W2077507754 cites W2051503189 @default.
• W2077507754 cites W2053810188 @default.
• W2077507754 cites W2062366058 @default.
• W2077507754 cites W2062944414 @default.
• W2077507754 cites W2072512993 @default.
• W2077507754 cites W2081335831 @default.
• W2077507754 cites W2083658535 @default.
• W2077507754 cites W2086470134 @default.
• W2077507754 cites W2087042268 @default.
• W2077507754 cites W2087689252 @default.
• W2077507754 cites W2097450722 @default.
• W2077507754 cites W2114988623 @default.
• W2077507754 cites W2122695220 @default.
• W2077507754 cites W2157640447 @default.
• W2077507754 cites W2158078521 @default.
• W2077507754 cites W2399607879 @default.
• W2077507754 cites W4254007910 @default.
• W2077507754 cites W4293247451 @default.
• W2077507754 cites W2079725546 @default.
• W2077507754 doi "https://doi.org/10.1016/j.bbapap.2009.08.011" @default.
• W2077507754 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19695351" @default.
• W2077507754 hasPublicationYear "2009" @default.
• W2077507754 type Work @default.
• W2077507754 sameAs 2077507754 @default.
• W2077507754 citedByCount "7" @default.
• W2077507754 countsByYear W20775077542012 @default.
• W2077507754 countsByYear W20775077542015 @default.
• W2077507754 countsByYear W20775077542023 @default.
• W2077507754 crossrefType "journal-article" @default.
• W2077507754 hasAuthorship W2077507754A5016590260 @default.
• W2077507754 hasAuthorship W2077507754A5035002495 @default.
• W2077507754 hasAuthorship W2077507754A5039253271 @default.
• W2077507754 hasAuthorship W2077507754A5055149878 @default.
• W2077507754 hasAuthorship W2077507754A5059176966 @default.
• W2077507754 hasAuthorship W2077507754A5077658470 @default.
• W2077507754 hasAuthorship W2077507754A5086418754 @default.
• W2077507754 hasConcept C162008176 @default.
• W2077507754 hasConcept C181199279 @default.
• W2077507754 hasConcept C185592680 @default.
• W2077507754 hasConcept C197957613 @default.
• W2077507754 hasConcept C202751555 @default.
• W2077507754 hasConcept C21951064 @default.
• W2077507754 hasConcept C2776120743 @default.
• W2077507754 hasConcept C2776145790 @default.
• W2077507754 hasConcept C2776338311 @default.
• W2077507754 hasConcept C55493867 @default.
• W2077507754 hasConcept C58808276 @default.
• W2077507754 hasConcept C71240020 @default.
• W2077507754 hasConcept C87554066 @default.
• W2077507754 hasConceptScore W2077507754C162008176 @default.
• W2077507754 hasConceptScore W2077507754C181199279 @default.
• W2077507754 hasConceptScore W2077507754C185592680 @default.
• W2077507754 hasConceptScore W2077507754C197957613 @default.
• W2077507754 hasConceptScore W2077507754C202751555 @default.
• W2077507754 hasConceptScore W2077507754C21951064 @default.
• W2077507754 hasConceptScore W2077507754C2776120743 @default.
• W2077507754 hasConceptScore W2077507754C2776145790 @default.
• W2077507754 hasConceptScore W2077507754C2776338311 @default.
• W2077507754 hasConceptScore W2077507754C55493867 @default.
• W2077507754 hasConceptScore W2077507754C58808276 @default.
• W2077507754 hasConceptScore W2077507754C71240020 @default.
• W2077507754 hasConceptScore W2077507754C87554066 @default.
• W2077507754 hasIssue "12" @default.
• W2077507754 hasLocation W20775077541 @default.
• W2077507754 hasLocation W20775077542 @default.
• W2077507754 hasOpenAccess W2077507754 @default.
• W2077507754 hasPrimaryLocation W20775077541 @default.
• W2077507754 hasRelatedWork W1493419455 @default.
• W2077507754 hasRelatedWork W1991461635 @default.
• W2077507754 hasRelatedWork W1999810095 @default.
• W2077507754 hasRelatedWork W2032852028 @default.

• next