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- W2077510116 abstract "Groups of brook trout (Salvelinus fontinalis) were fed a polychlorinated biphenyl (PCB) mixture (Aroclor 1254) or three PCB replacements based on phenylxylylethane or diisopropylnaphthalene mixtures at dose levels of 30 and 100 μg·g−1. Both dose levels of all the materials tested induced hepatic ethoxyresorufin O-deethylase activity; ethoxycoumarin O-deethylase activity was induced by Aroclor 1254 and one of the phenylxylylethane mixtures. Benzphetamine N-demethylase activity was not induced by any treatment. Effects on other indices of MFO induction, such as protein content and cytochrome P-450 content, were variable. The fish accumulated from 13 to 46% of the Aroclor 1254 dose but only 2 to 7% of the PCB replacements. All components of the phenylxylylethane mixtures were accumulated but some major components of the diisopropylnaphthalenes were not." @default.
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- W2077510116 date "1982-04-01" @default.
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- W2077510116 title "Induction of hepatic mixed function oxidase activity in trout (Salvelinus fontinalis) by Aroclor 1254 and some aromatic hydrocarbon PCB replacements" @default.
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- W2077510116 doi "https://doi.org/10.1016/0041-008x(82)90037-0" @default.
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