Matches in SemOpenAlex for { <https://semopenalex.org/work/W2077519232> ?p ?o ?g. }
- W2077519232 abstract "We have performed an atomistic molecular dynamics simulation of an aqueous solution of hen egg-white lysozyme at room temperature with explicit water molecules. Several analyses have been carried out to explore the differential flexibility of the secondary structural segments of the protein and the structure and ordering of water around them. It is found that the overall flexibility of the protein molecule is primarily controlled by few large-amplitude bistable motions exhibited by two coils; one connecting two α-helical segments in domain-1 and the other connecting a 3(10) helix and a β-sheet in domain-2 of the protein. The heterogeneous structuring of water around the segments of the protein has been found to depend on the degree of exposure of the segments to water. The ordering of water molecules around the protein segments and their tagged potential energies have been found to be anticorrelated with each other. Some of these findings can be verified by suitable experimental studies." @default.
- W2077519232 created "2016-06-24" @default.
- W2077519232 creator A5042455024 @default.
- W2077519232 creator A5051434187 @default.
- W2077519232 date "2011-03-16" @default.
- W2077519232 modified "2023-09-27" @default.
- W2077519232 title "Differential flexibility of the secondary structures of lysozyme and the structure and ordering of surrounding water molecules" @default.
- W2077519232 cites W138398165 @default.
- W2077519232 cites W1537479324 @default.
- W2077519232 cites W1963707717 @default.
- W2077519232 cites W1968386558 @default.
- W2077519232 cites W1968472876 @default.
- W2077519232 cites W1968704773 @default.
- W2077519232 cites W1972218666 @default.
- W2077519232 cites W1974030600 @default.
- W2077519232 cites W1976499671 @default.
- W2077519232 cites W1979399409 @default.
- W2077519232 cites W1991775910 @default.
- W2077519232 cites W1994153968 @default.
- W2077519232 cites W1997555833 @default.
- W2077519232 cites W1998169010 @default.
- W2077519232 cites W1999223285 @default.
- W2077519232 cites W2001614166 @default.
- W2077519232 cites W2002104120 @default.
- W2077519232 cites W2005246178 @default.
- W2077519232 cites W2016487696 @default.
- W2077519232 cites W2018614955 @default.
- W2077519232 cites W2018625724 @default.
- W2077519232 cites W2026361230 @default.
- W2077519232 cites W2027408247 @default.
- W2077519232 cites W2031091369 @default.
- W2077519232 cites W2033030280 @default.
- W2077519232 cites W2033761929 @default.
- W2077519232 cites W2038758364 @default.
- W2077519232 cites W2045773045 @default.
- W2077519232 cites W2046515692 @default.
- W2077519232 cites W2049187746 @default.
- W2077519232 cites W2057047042 @default.
- W2077519232 cites W2057742133 @default.
- W2077519232 cites W2058862385 @default.
- W2077519232 cites W2061175110 @default.
- W2077519232 cites W2067012477 @default.
- W2077519232 cites W2067174909 @default.
- W2077519232 cites W2069558639 @default.
- W2077519232 cites W2069586413 @default.
- W2077519232 cites W2072043602 @default.
- W2077519232 cites W2074468510 @default.
- W2077519232 cites W2077480295 @default.
- W2077519232 cites W2078216776 @default.
- W2077519232 cites W2084316830 @default.
- W2077519232 cites W2084834685 @default.
- W2077519232 cites W2087050367 @default.
- W2077519232 cites W2089608829 @default.
- W2077519232 cites W2094410679 @default.
- W2077519232 cites W2094447806 @default.
- W2077519232 cites W2094493821 @default.
- W2077519232 cites W2142706107 @default.
- W2077519232 cites W2144062946 @default.
- W2077519232 cites W2144927313 @default.
- W2077519232 cites W2145215567 @default.
- W2077519232 cites W2150981663 @default.
- W2077519232 cites W2161908442 @default.
- W2077519232 cites W2167404361 @default.
- W2077519232 cites W2167506192 @default.
- W2077519232 doi "https://doi.org/10.1063/1.3560442" @default.
- W2077519232 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21428665" @default.
- W2077519232 hasPublicationYear "2011" @default.
- W2077519232 type Work @default.
- W2077519232 sameAs 2077519232 @default.
- W2077519232 citedByCount "28" @default.
- W2077519232 countsByYear W20775192322012 @default.
- W2077519232 countsByYear W20775192322013 @default.
- W2077519232 countsByYear W20775192322014 @default.
- W2077519232 countsByYear W20775192322015 @default.
- W2077519232 countsByYear W20775192322016 @default.
- W2077519232 countsByYear W20775192322017 @default.
- W2077519232 countsByYear W20775192322018 @default.
- W2077519232 countsByYear W20775192322019 @default.
- W2077519232 countsByYear W20775192322020 @default.
- W2077519232 countsByYear W20775192322022 @default.
- W2077519232 countsByYear W20775192322023 @default.
- W2077519232 crossrefType "journal-article" @default.
- W2077519232 hasAuthorship W2077519232A5042455024 @default.
- W2077519232 hasAuthorship W2077519232A5051434187 @default.
- W2077519232 hasBestOaLocation W20775192321 @default.
- W2077519232 hasConcept C105795698 @default.
- W2077519232 hasConcept C147597530 @default.
- W2077519232 hasConcept C147789679 @default.
- W2077519232 hasConcept C159467904 @default.
- W2077519232 hasConcept C178790620 @default.
- W2077519232 hasConcept C184651966 @default.
- W2077519232 hasConcept C185592680 @default.
- W2077519232 hasConcept C192562407 @default.
- W2077519232 hasConcept C2776966407 @default.
- W2077519232 hasConcept C2780598303 @default.
- W2077519232 hasConcept C32909587 @default.
- W2077519232 hasConcept C33923547 @default.
- W2077519232 hasConcept C47701112 @default.
- W2077519232 hasConcept C49040817 @default.
- W2077519232 hasConcept C55493867 @default.