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- W2077534701 abstract "The conclusions made by Shmerling and Delbanco 1 regarding the utility of rheumatoid factor (RF) in the diagnosis of rheumatoid arthritis (RA) came as a bit of a surprise, seemingly reversing conventional thinking. Although we can agree, based on their data, that RF is, at times, ordered inappropriately (ie, in the absence of joint complaints), we find it difficult toaccept the study's estimates for sensitivity (28%), specificity (87%), and positive predictive value (24%). Kelley et al 2 quote 70% sensitivity of the RF for RA, and Wolfe et al 3 quote 81.6%. We examined the study by Shmerling and Delbanco to locate possible explanations for this discrepancy. The gold standard for the diagnosis of RA in the study was the use of chart review, applying the American Rheumatism Association's remaining six guidelines (excluding the RF). 1 By this method, they claim to have discovered 10 seronegative RA patients out" @default.
- W2077534701 created "2016-06-24" @default.
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- W2077534701 date "1993-08-23" @default.
- W2077534701 modified "2023-09-25" @default.
- W2077534701 title "The Utility of the Rheumatoid Factor" @default.
- W2077534701 cites W1597479768 @default.
- W2077534701 cites W1998399396 @default.
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- W2077534701 doi "https://doi.org/10.1001/archinte.1993.00410160111013" @default.
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