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• W2077543399 abstract "Osteoporosis is a major public health threat. Multiple studies have reported an association between depression and low bone mineral density, but a causal link between these two conditions is disputed. Here we review the endocrine and immune alterations secondary to depression that might affect bone mass. We also discuss the possible role of poor lifestyle in the etiology of osteoporosis in subjects with depression and the potential effect of antidepressants on bone loss. We propose that depression induces bone loss and osteoporotic fractures, primarily via specific immune and endocrine mechanisms, while poor lifestyle habits and use of specific antidepressants are potential contributory factors." @default.
• W2077543399 created "2016-06-24" @default.
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• W2077543399 date "2009-10-01" @default.
• W2077543399 modified "2023-10-14" @default.
• W2077543399 title "Depression as a risk factor for osteoporosis" @default.
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• W2077543399 doi "https://doi.org/10.1016/j.tem.2009.05.003" @default.
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• W2077543399 hasPublicationYear "2009" @default.
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