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• W2077545486 abstract "Purpose of review Eczema and other allergic disorders are complex diseases caused by multiple genetic and environmental factors. Here, we review recent success in the identification of novel susceptibility loci for eczema. Recent findings Genome-wide association studies led to marked progress in unraveling the genetic determinants of allergic disorders. In the past 4 years, a total of 14 new eczema susceptibility loci have been identified and nearly all of them were successfully replicated. Seven additional eczema loci were recently identified by alternative strategies utilizing the remarkable overlap in the genetic cause of diverse immune-related traits. Apart from underlining the importance of the skin barrier in eczema, these studies point to specific immunological functions altered in eczema pathogenesis. Summary The new findings demonstrate that common pathways are involved in the development of eczema and other immune-related traits. Moreover, the genetic determinants shared between eczema, asthma, and allergic rhinitis should aid in resolving the molecular mechanisms triggering disease progression along the atopic march. The identification of the underlying genes and causal variants will be the major challenge for upcoming studies." @default.
• W2077545486 created "2016-06-24" @default.
• W2077545486 creator A5006437153 @default.
• W2077545486 creator A5061487444 @default.
• W2077545486 creator A5082340383 @default.
• W2077545486 date "2013-10-01" @default.
• W2077545486 modified "2023-10-02" @default.
• W2077545486 title "Shared genetic determinants between eczema and other immune-related diseases" @default.
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• W2077545486 cites W1963639770 @default.
• W2077545486 cites W1965641017 @default.
• W2077545486 cites W1965727970 @default.
• W2077545486 cites W1977544016 @default.
• W2077545486 cites W1978150238 @default.
• W2077545486 cites W1980284146 @default.
• W2077545486 cites W1983312277 @default.
• W2077545486 cites W1985021863 @default.
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• W2077545486 cites W1993255002 @default.
• W2077545486 cites W1999639094 @default.
• W2077545486 cites W1999690368 @default.
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• W2077545486 doi "https://doi.org/10.1097/aci.0b013e328364e8f7" @default.
• W2077545486 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23945175" @default.
• W2077545486 hasPublicationYear "2013" @default.
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