Matches in SemOpenAlex for { <https://semopenalex.org/work/W2077574676> ?p ?o ?g. }
- W2077574676 endingPage "1188" @default.
- W2077574676 startingPage "1180" @default.
- W2077574676 abstract "Objective Premenopausal women demonstrate a distinctive gynoid body fat distribution and circulating estrogen status is associated with the maintenance of this adiposity patterning. Estrogen's role in modulation of regional adiposity may occur through estrogen receptors (ERs), which are present in human adipose tissue. The purpose of this study was to determine regional differences in the protein content of ERα, ERβ, and the G protein-coupled estrogen receptor (GPER) between the abdominal (AB) and gluteal (GL) subcutaneous adipose tissue of overweight-to-obese premenopausal women. Materials/Methods Biopsies of the subcutaneous AB and GL adipose tissue were performed in 15 premenopausal women (7 Caucasian/8 African American, 25.1 ± 1.8 years, BMI 29.5 ± 0.5 kg/m2). Adipose tissue protein content was measured by western blot analysis and correlation analyses were conducted to assess the relationship between ER protein content and anthropometric indices/body composition measurements. Results We found that ERα protein was higher in AB than GL (AB 1.0 ± 0.2 vs GL 0.67 ± 0.1 arbitrary units [AU], P = 0.02), ERβ protein was higher in GL than AB (AB 0.78 ± 0.12 vs GL 1.3 ± 0.2 AU, P = 0.002), ERα/ERβ ratio was higher in AB than GL (AB 1.9 ± 0.4 vs GL 0.58 ± 0.08 AU, P = 0.007), and GPER protein content was similar in AB and GL (P = 0.80) subcutaneous adipose tissue. Waist-to-hip ratio was inversely related to gluteal ERβ (r2 = 0.315, P = 0.03) and positively related to gluteal ERα/ERβ ratio (r2 = 0.406, P = 0.01). Conclusions These results indicate that depot specific ER content may be an important underlying determinant of regional effects of estrogen in upper and lower body adipose tissue of overweight-to-obese premenopausal women." @default.
- W2077574676 created "2016-06-24" @default.
- W2077574676 creator A5035043190 @default.
- W2077574676 creator A5039219380 @default.
- W2077574676 creator A5077559278 @default.
- W2077574676 date "2013-08-01" @default.
- W2077574676 modified "2023-10-02" @default.
- W2077574676 title "Estrogen receptor protein content is different in abdominal than gluteal subcutaneous adipose tissue of overweight-to-obese premenopausal women" @default.
- W2077574676 cites W1768018877 @default.
- W2077574676 cites W1966734409 @default.
- W2077574676 cites W1969088839 @default.
- W2077574676 cites W1970784784 @default.
- W2077574676 cites W1976775669 @default.
- W2077574676 cites W1986795114 @default.
- W2077574676 cites W1990952279 @default.
- W2077574676 cites W1991455388 @default.
- W2077574676 cites W2009089225 @default.
- W2077574676 cites W2012070955 @default.
- W2077574676 cites W2013033239 @default.
- W2077574676 cites W2021420556 @default.
- W2077574676 cites W2022094463 @default.
- W2077574676 cites W2022965804 @default.
- W2077574676 cites W2038686627 @default.
- W2077574676 cites W2041083411 @default.
- W2077574676 cites W2056475677 @default.
- W2077574676 cites W2060025135 @default.
- W2077574676 cites W2060680663 @default.
- W2077574676 cites W2061510535 @default.
- W2077574676 cites W2064176291 @default.
- W2077574676 cites W2065707820 @default.
- W2077574676 cites W2068519004 @default.
- W2077574676 cites W2069684137 @default.
- W2077574676 cites W2078152943 @default.
- W2077574676 cites W2081021830 @default.
- W2077574676 cites W2081210725 @default.
- W2077574676 cites W2089398850 @default.
- W2077574676 cites W2100917763 @default.
- W2077574676 cites W2111230909 @default.
- W2077574676 cites W2113576333 @default.
- W2077574676 cites W2114208804 @default.
- W2077574676 cites W2115460245 @default.
- W2077574676 cites W2116404316 @default.
- W2077574676 cites W2118689874 @default.
- W2077574676 cites W2120758873 @default.
- W2077574676 cites W2130957039 @default.
- W2077574676 cites W2132018726 @default.
- W2077574676 cites W2136587076 @default.
- W2077574676 cites W2141759136 @default.
- W2077574676 cites W2146975650 @default.
- W2077574676 cites W2151172917 @default.
- W2077574676 cites W2167154664 @default.
- W2077574676 cites W2347041302 @default.
- W2077574676 cites W4249852060 @default.
- W2077574676 doi "https://doi.org/10.1016/j.metabol.2013.02.010" @default.
- W2077574676 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23557590" @default.
- W2077574676 hasPublicationYear "2013" @default.
- W2077574676 type Work @default.
- W2077574676 sameAs 2077574676 @default.
- W2077574676 citedByCount "35" @default.
- W2077574676 countsByYear W20775746762014 @default.
- W2077574676 countsByYear W20775746762015 @default.
- W2077574676 countsByYear W20775746762016 @default.
- W2077574676 countsByYear W20775746762017 @default.
- W2077574676 countsByYear W20775746762018 @default.
- W2077574676 countsByYear W20775746762019 @default.
- W2077574676 countsByYear W20775746762020 @default.
- W2077574676 countsByYear W20775746762021 @default.
- W2077574676 countsByYear W20775746762022 @default.
- W2077574676 countsByYear W20775746762023 @default.
- W2077574676 crossrefType "journal-article" @default.
- W2077574676 hasAuthorship W2077574676A5035043190 @default.
- W2077574676 hasAuthorship W2077574676A5039219380 @default.
- W2077574676 hasAuthorship W2077574676A5077559278 @default.
- W2077574676 hasConcept C121608353 @default.
- W2077574676 hasConcept C126322002 @default.
- W2077574676 hasConcept C134018914 @default.
- W2077574676 hasConcept C166471694 @default.
- W2077574676 hasConcept C171089720 @default.
- W2077574676 hasConcept C185592680 @default.
- W2077574676 hasConcept C2776193436 @default.
- W2077574676 hasConcept C2777164284 @default.
- W2077574676 hasConcept C2780586474 @default.
- W2077574676 hasConcept C2908640109 @default.
- W2077574676 hasConcept C511355011 @default.
- W2077574676 hasConcept C530470458 @default.
- W2077574676 hasConcept C71924100 @default.
- W2077574676 hasConcept C84606932 @default.
- W2077574676 hasConceptScore W2077574676C121608353 @default.
- W2077574676 hasConceptScore W2077574676C126322002 @default.
- W2077574676 hasConceptScore W2077574676C134018914 @default.
- W2077574676 hasConceptScore W2077574676C166471694 @default.
- W2077574676 hasConceptScore W2077574676C171089720 @default.
- W2077574676 hasConceptScore W2077574676C185592680 @default.
- W2077574676 hasConceptScore W2077574676C2776193436 @default.
- W2077574676 hasConceptScore W2077574676C2777164284 @default.
- W2077574676 hasConceptScore W2077574676C2780586474 @default.
- W2077574676 hasConceptScore W2077574676C2908640109 @default.
- W2077574676 hasConceptScore W2077574676C511355011 @default.