Matches in SemOpenAlex for { <https://semopenalex.org/work/W2077576411> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W2077576411 endingPage "1836" @default.
- W2077576411 startingPage "1828" @default.
- W2077576411 abstract "Different experimental strategies using short columns in both conventional liquid chromatography (HPLC) and ultra-high pressure liquid chromatography (UHPLC) were evaluated to allow, for the first time with these techniques, the lipophilicity determination of compounds with log P>5. Various organic modifiers, stationary phases, and elution modes were tested on 14 rigid compounds with a CLogP between 5 and 8, and 38 compounds with log P(oct) from 0 to 5. The best results in HPLC were obtained with the 20-mm Discovery RP Amide C16 stationary phase in isocratic mode using MeOH as organic modifier. To improve analysis time, the UHPLC approach was then evaluated. Consequently, a generic method was developed with a 30-mm Acquity BEH Shield RP18 column in gradient mode using MeOH as organic modifier, allowing a fourfold gain of time compared to the HPLC method, for the highly lipophilic compounds tested. Finally, the most rapid and accurate results were obtained with a 10-mm Hypersil GOLD Javelin HTS stationary phase in UHPLC, enabling an eightfold gain of time compared to the HPLC method." @default.
- W2077576411 created "2016-06-24" @default.
- W2077576411 creator A5001491891 @default.
- W2077576411 creator A5003426636 @default.
- W2077576411 creator A5014486326 @default.
- W2077576411 creator A5050596312 @default.
- W2077576411 creator A5067528218 @default.
- W2077576411 creator A5074153377 @default.
- W2077576411 creator A5079241702 @default.
- W2077576411 date "2009-11-01" @default.
- W2077576411 modified "2023-10-18" @default.
- W2077576411 title "Lipophilicity Determination of Highly Lipophilic Compounds by Liquid Chromatography" @default.
- W2077576411 cites W1980320892 @default.
- W2077576411 cites W1987258334 @default.
- W2077576411 cites W2005940893 @default.
- W2077576411 cites W2017811176 @default.
- W2077576411 cites W2028551469 @default.
- W2077576411 cites W2049631254 @default.
- W2077576411 cites W2051926820 @default.
- W2077576411 cites W2065163726 @default.
- W2077576411 cites W2073142769 @default.
- W2077576411 cites W2075671346 @default.
- W2077576411 cites W2078664206 @default.
- W2077576411 cites W2080213998 @default.
- W2077576411 cites W2084787355 @default.
- W2077576411 cites W2133324570 @default.
- W2077576411 cites W2317261051 @default.
- W2077576411 doi "https://doi.org/10.1002/cbdv.200900115" @default.
- W2077576411 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19937824" @default.
- W2077576411 hasPublicationYear "2009" @default.
- W2077576411 type Work @default.
- W2077576411 sameAs 2077576411 @default.
- W2077576411 citedByCount "27" @default.
- W2077576411 countsByYear W20775764112012 @default.
- W2077576411 countsByYear W20775764112013 @default.
- W2077576411 countsByYear W20775764112014 @default.
- W2077576411 countsByYear W20775764112016 @default.
- W2077576411 countsByYear W20775764112017 @default.
- W2077576411 countsByYear W20775764112018 @default.
- W2077576411 countsByYear W20775764112020 @default.
- W2077576411 countsByYear W20775764112022 @default.
- W2077576411 countsByYear W20775764112023 @default.
- W2077576411 crossrefType "journal-article" @default.
- W2077576411 hasAuthorship W2077576411A5001491891 @default.
- W2077576411 hasAuthorship W2077576411A5003426636 @default.
- W2077576411 hasAuthorship W2077576411A5014486326 @default.
- W2077576411 hasAuthorship W2077576411A5050596312 @default.
- W2077576411 hasAuthorship W2077576411A5067528218 @default.
- W2077576411 hasAuthorship W2077576411A5074153377 @default.
- W2077576411 hasAuthorship W2077576411A5079241702 @default.
- W2077576411 hasConcept C178790620 @default.
- W2077576411 hasConcept C179998833 @default.
- W2077576411 hasConcept C185592680 @default.
- W2077576411 hasConcept C201399114 @default.
- W2077576411 hasConcept C43617362 @default.
- W2077576411 hasConcept C45188465 @default.
- W2077576411 hasConceptScore W2077576411C178790620 @default.
- W2077576411 hasConceptScore W2077576411C179998833 @default.
- W2077576411 hasConceptScore W2077576411C185592680 @default.
- W2077576411 hasConceptScore W2077576411C201399114 @default.
- W2077576411 hasConceptScore W2077576411C43617362 @default.
- W2077576411 hasConceptScore W2077576411C45188465 @default.
- W2077576411 hasIssue "11" @default.
- W2077576411 hasLocation W20775764111 @default.
- W2077576411 hasLocation W20775764112 @default.
- W2077576411 hasOpenAccess W2077576411 @default.
- W2077576411 hasPrimaryLocation W20775764111 @default.
- W2077576411 hasRelatedWork W1534137913 @default.
- W2077576411 hasRelatedWork W1550666270 @default.
- W2077576411 hasRelatedWork W1970870379 @default.
- W2077576411 hasRelatedWork W1976607297 @default.
- W2077576411 hasRelatedWork W2039531209 @default.
- W2077576411 hasRelatedWork W2081306075 @default.
- W2077576411 hasRelatedWork W2163082733 @default.
- W2077576411 hasRelatedWork W2417209194 @default.
- W2077576411 hasRelatedWork W2524959782 @default.
- W2077576411 hasRelatedWork W2601117855 @default.
- W2077576411 hasVolume "6" @default.
- W2077576411 isParatext "false" @default.
- W2077576411 isRetracted "false" @default.
- W2077576411 magId "2077576411" @default.
- W2077576411 workType "article" @default.