FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2077599013> ?p ?o ?g. }

• W2077599013 endingPage "110" @default.
• W2077599013 startingPage "97" @default.
• W2077599013 abstract "Laminin-associated polypeptide 2 (LAP2) proteins are alternatively spliced products of a single gene; they belong to the LEM domain family and, in mammals, locate to the nuclear envelope (NE) and nuclear lamina. Isoforms lacking the transmembrane domain also locate to the nucleoplasm. We used new specific antibodies against the N-terminal domain of Xenopus LAP2 to perform immunoprecipitation, identification and localization studies during Xenopus development. By immunoprecipitation and mass spectrometry (LC/MS/MS), we identified the embryonic isoform XLAP2γ, which was downregulated during development similarly to XLAP2ω. Embryonic isoforms XLAP2ω and XLAP2γ were located in close association with chromatin up to the blastula stage. Later in development, both embryonic isoforms and the adult isoform XLAP2β were localized in a similar way at the NE. All isoforms colocalized with lamin B2/B3 during development, whereas XLAP2β was colocalized with lamin B2 and apparently with the F/G repeat nucleoporins throughout the cell cycle in adult tissues and culture cells. XLAP2β was localized in clusters on chromatin, both at the NE and inside the nucleus. Embryonic isoforms were also localized in clusters at the NE of oocytes. Our results suggest that XLAP2 isoforms participate in the maintenance and anchoring of chromatin domains to the NE and in the formation of lamin B microdomains." @default.
• W2077599013 created "2016-06-24" @default.
• W2077599013 creator A5008940626 @default.
• W2077599013 creator A5022106920 @default.
• W2077599013 creator A5028681511 @default.
• W2077599013 creator A5037056375 @default.
• W2077599013 creator A5037898159 @default.
• W2077599013 creator A5071876542 @default.
• W2077599013 creator A5091848433 @default.
• W2077599013 date "2011-02-24" @default.
• W2077599013 modified "2023-10-01" @default.
• W2077599013 title "Embryonic and adult isoforms of XLAP2 form microdomains associated with chromatin and the nuclear envelope" @default.
• W2077599013 cites W1514903902 @default.
• W2077599013 cites W1703665345 @default.
• W2077599013 cites W1845088912 @default.
• W2077599013 cites W1912203081 @default.
• W2077599013 cites W1923070576 @default.
• W2077599013 cites W1965168929 @default.
• W2077599013 cites W1969298304 @default.
• W2077599013 cites W1997476399 @default.
• W2077599013 cites W2008627600 @default.
• W2077599013 cites W2009170691 @default.
• W2077599013 cites W2016589083 @default.
• W2077599013 cites W2020212714 @default.
• W2077599013 cites W2040917348 @default.
• W2077599013 cites W2042791963 @default.
• W2077599013 cites W2056204193 @default.
• W2077599013 cites W2056367986 @default.
• W2077599013 cites W2057901296 @default.
• W2077599013 cites W2058162240 @default.
• W2077599013 cites W2058189036 @default.
• W2077599013 cites W2083507591 @default.
• W2077599013 cites W2094615509 @default.
• W2077599013 cites W2096354772 @default.
• W2077599013 cites W2098878044 @default.
• W2077599013 cites W2103330925 @default.
• W2077599013 cites W2109507594 @default.
• W2077599013 cites W2109943932 @default.
• W2077599013 cites W2123657399 @default.
• W2077599013 cites W2131593425 @default.
• W2077599013 cites W2131840166 @default.
• W2077599013 cites W2134915506 @default.
• W2077599013 cites W2136583609 @default.
• W2077599013 cites W2143126673 @default.
• W2077599013 cites W2149328454 @default.
• W2077599013 cites W2187950101 @default.
• W2077599013 doi "https://doi.org/10.1007/s00441-011-1129-2" @default.
• W2077599013 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3112025" @default.
• W2077599013 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21347574" @default.
• W2077599013 hasPublicationYear "2011" @default.
• W2077599013 type Work @default.
• W2077599013 sameAs 2077599013 @default.
• W2077599013 citedByCount "8" @default.
• W2077599013 countsByYear W20775990132012 @default.
• W2077599013 countsByYear W20775990132014 @default.
• W2077599013 countsByYear W20775990132015 @default.
• W2077599013 countsByYear W20775990132017 @default.
• W2077599013 countsByYear W20775990132018 @default.
• W2077599013 countsByYear W20775990132019 @default.
• W2077599013 crossrefType "journal-article" @default.
• W2077599013 hasAuthorship W2077599013A5008940626 @default.
• W2077599013 hasAuthorship W2077599013A5022106920 @default.
• W2077599013 hasAuthorship W2077599013A5028681511 @default.
• W2077599013 hasAuthorship W2077599013A5037056375 @default.
• W2077599013 hasAuthorship W2077599013A5037898159 @default.
• W2077599013 hasAuthorship W2077599013A5071876542 @default.
• W2077599013 hasAuthorship W2077599013A5091848433 @default.
• W2077599013 hasBestOaLocation W20775990131 @default.
• W2077599013 hasConcept C104317684 @default.
• W2077599013 hasConcept C112952253 @default.
• W2077599013 hasConcept C145103041 @default.
• W2077599013 hasConcept C153911025 @default.
• W2077599013 hasConcept C179093185 @default.
• W2077599013 hasConcept C183873130 @default.
• W2077599013 hasConcept C190062978 @default.
• W2077599013 hasConcept C2779535977 @default.
• W2077599013 hasConcept C2780723820 @default.
• W2077599013 hasConcept C2781023310 @default.
• W2077599013 hasConcept C29512474 @default.
• W2077599013 hasConcept C53345823 @default.
• W2077599013 hasConcept C54355233 @default.
• W2077599013 hasConcept C71829478 @default.
• W2077599013 hasConcept C83640560 @default.
• W2077599013 hasConcept C86339819 @default.
• W2077599013 hasConcept C86803240 @default.
• W2077599013 hasConcept C94912109 @default.
• W2077599013 hasConcept C95444343 @default.
• W2077599013 hasConceptScore W2077599013C104317684 @default.
• W2077599013 hasConceptScore W2077599013C112952253 @default.
• W2077599013 hasConceptScore W2077599013C145103041 @default.
• W2077599013 hasConceptScore W2077599013C153911025 @default.
• W2077599013 hasConceptScore W2077599013C179093185 @default.
• W2077599013 hasConceptScore W2077599013C183873130 @default.
• W2077599013 hasConceptScore W2077599013C190062978 @default.
• W2077599013 hasConceptScore W2077599013C2779535977 @default.
• W2077599013 hasConceptScore W2077599013C2780723820 @default.
• W2077599013 hasConceptScore W2077599013C2781023310 @default.
• W2077599013 hasConceptScore W2077599013C29512474 @default.

• next