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• W2077653019 abstract "In order to identify the role of the bovine herpesvirus type 1 (BHV-1) glycoprotein E (gE) in the viral infection cycle, we have constructed a BHV-1 gE deletion mutant strain (BHV-1 gE−. This strain was assayed in vitro by comparing its growth kinetics with the wild type strain used as a host of the deletion. Our results indicate that those conditions which prevent the infection by direct adsorption to the cells (presence of a semi-solid medium or presence of neutralizing antibodies in the medium) selectively inhibit the growth of the gE− strain, suggesting that gE plays a central role in the BHV-1 spread by direct cell-to-cell transmission, a major mechanism of the BHV-1 in vivo virulence." @default.
• W2077653019 created "2016-06-24" @default.
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• W2077653019 date "1996-11-01" @default.
• W2077653019 modified "2023-09-23" @default.
• W2077653019 title "Glycoprotein E of bovine herpesvirus type 1 is involved in virus transmission by direct cell-to-cell spread" @default.
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• W2077653019 doi "https://doi.org/10.1016/0168-1702(96)01353-6" @default.
• W2077653019 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8896241" @default.
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