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• W2077682912 abstract "Abstract A pulse sequence is described serving the volume-selective editing of resonances in biomedical NMR spectroscopy. The editing principle is the temporary transfer of polarization of the spins to be detected to other spin species coupled to them. The pulse sequence providing this cyclic polarization transfer (CYCLPOT) can be used as a module to be incorporated in general pulse sequence frames. An example is the VOSY family of volume-selective spectroscopy techniques applied for the localized detection of the lactate methyl proton line while spoiling coherences of the lipid nuclei otherwise overlapping the lactate resonance. The whole-line editing and coherence spoiling procedure takes place completely in each scan of any accumulation or phase-cycling series. The technique has been tested under artificial as well as under simulated in vivo conditions. Furthermore the measurement of the longitudinal and transverse relaxation times of the volume selectively edited resonance line is demonstrated. Thus parameters promising additional information of biomedical interest become accessible. This also provides the possibility to correct line intensities for relaxation effects as an essential prerequisite for the precise determination of concentrations." @default.
• W2077682912 created "2016-06-24" @default.
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• W2077682912 date "1989-06-01" @default.
• W2077682912 modified "2023-09-27" @default.
• W2077682912 title "Cyclic polarization transfer and a new technique for volume-selective single-scan spectral editing and relaxometry of proton spectra" @default.
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• W2077682912 doi "https://doi.org/10.1016/0022-2364(89)90195-9" @default.
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